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127005 trials found · Page 5666 of 6351
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New monitoring method may help doctors manage blood pressure during heart surgery
Knowledge-focused CompletedCentral and peripheral arterial pressure decoupling occurs in some clinical conditions like sepsis or cardiopulmonary bypass. This decoupling may leed to unsuitable decisions such as the use of catecholamines. The aim of this study is to evaluate the pulse wave's speed as a mark…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:01 UTC
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Researchers track rare artery disease affecting the lungs
Knowledge-focused Recruiting nowThe purpose of this study is to identify the clinical features, management pattern and long-term outcomes of patients with pulmonary arteries involvement in Takayasu's arteritis (TAK-PAI).
Sponsor: China-Japan Friendship Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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30,000 HIV patients enrolled in massive french observational study
Knowledge-focused Recruiting nowThe objective of the Dataids cohort is to continue a long-term, prospective collection of clinical, laboratory and therapeutic data on a large cohort of HIV infected patients seeking care in 15 HIV centers in France in order : 1. to provide and develop a surveillance system to d…
Sponsor: DatAids • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Million-Person study aims to uncover disease patterns in rural china
Knowledge-focused Recruiting nowThis population-based cohort study on disease prevention and health promotion was established in northwest China, leveraging data from routine annual health examinations. Initiated in January 2016, the cohort enrolled nearly all residents aged 18 years and older who were register…
Sponsor: People's Hospital of Xinjiang Uygur Autonomous Region • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Blood protein may hold key to unexplained miscarriages and IVF failures
Knowledge-focused Recruiting nowA low plasma level of mannose binding lectin (p-MBL) is associated with unexplained recurrent pregnancy loss (RPL), but it is not investigated if it is associated with unexplained reproductive failure in general, including recurrent implantation failure (RIF) after assisted repro…
Sponsor: Aalborg University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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New protocol may boost vaginal birth success after two C-Sections
Knowledge-focused Recruiting nowIn 2015 ObGyn Dept of Santo Spirito Hospital in Pescara (Italy) started protocol for previous CS vaginal birth. In 2021 was started a protocol for training on obstetric emergencies and protocol on two previous cesarean was endorsed. Patients attending birth in Pescara with two pr…
Sponsor: G. d'Annunzio University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Smartwatches and video calls could ease cancer care for rural patients
Symptom relief CompletedObservational study about patients treated for a metastasis breast cancer who live far from their comprehensive cancer center and followed by telemedicine, connected watches and patient-reported symptom monitoring.
Sponsor: Institut Bergonié • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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10,000 patients join hunt to tame deadly inflammation after aortic tear
Knowledge-focused Recruiting nowAcute aortic syndrome (AAS) is a life-threatening condition. Inflammation plays a key role in the pathogenesis, development and progression of AAS, and is associated with significant mortality and morbidity. Understanding the inflammatory responses and inflammation resolutions is…
Sponsor: Nanjing Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Gene hunt: 689 volunteers help unlock cancer clues
Knowledge-focused OngoingThis study is being done to learn more about how changes in certain genes may be linked to cancer. Some people with cancer got their disease because they inherited an abnormal (mutated) gene. The researchers of this study want to better understand the risks that are linked to ge…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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3,500 patients studied to uncover hidden effects of pancreas surgery
Knowledge-focused Recruiting nowPancreatic diseases often require surgery or invasive procedures to provide a chance for a cure. However, due to the pancreas's unique anatomical structure, its relative position to adjacent organs, and its dual endocrine and exocrine functions, the complexity of surgery is incre…
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Scientists probe brain and genes to unlock schizophrenia secrets
Knowledge-focused Recruiting nowThis study focuses on the structure and function of the brain and gene expression in peripheral blood of patients with schizophrenia, to explore the interaction and influence between the three. Patients with mental disorders who have been recruited will take their medication regu…
Sponsor: mingjun Zhong • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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New study aims to unravel balance secrets in spine patients
Knowledge-focused Recruiting nowA good understanding of the principles of balance is vital to achieve optimal outcomes when treating spinal disorders. A complex interaction of the neuromotor system and muscular recruitment is necessary for ergonomic balance and deliberate displacement of the human body. Sagitta…
Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Tiny study probes rare pancreatitis after clot removal
Knowledge-focused Recruiting nowAcute pancreatitis is a rare complication after percutaneous mechanical thrombectomy in treatment of thrombotic disorders. The objectives of this study include: (1) Determine the incidence and severity of acute pancreatitis after percutaneous mechanical thrombectomy; (2) Identify…
Sponsor: RenJi Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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New study aims to spot lung transplant trouble early
Knowledge-focused CompletedLung transplantation has become a promising therapeutic option for various end-stage lung diseases. However, many factors such as infection, graft rejection, airway complications would cause deterioration and shorten the survival time. It is important to detect the deterioration …
Sponsor: The First Affiliated Hospital of Guangzhou Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Simple blood draw may spot brain damage in mild head injuries
Knowledge-focused CompletedThe aim of this study is to investigate the early serum measurement (\<6h after injury) of mRNA miR Let-7i, miR-16 and miR-92 in patients with MHI and intracranial traumatic lesions (CCT pos.) as compared to those in patients with MHI without intracranial traumatic lesions (CCT n…
Sponsor: Harald Wolf, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Which rectal cancer treatment leads to better surgery outcomes?
Knowledge-focused CompletedAim: We evaluated the surgical outcomes of 3 groups of patients with rectal cancers - RAPIDO vs standard long course radiotherapy (LCRT) vs upfront surgery to objectively determine the effects of TNT on TME. Methods: A review of prospectively collected data was performed for pat…
Sponsor: Sengkang General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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Ultrasound at the bedside: a game changer for septic shock?
Knowledge-focused CompletedThis study aims to evaluate the clinical impact of the systematic implementation of point-of-care ultrasound (POCUS) in the management of patients with septic shock in the intensive care unit (ICU). Septic shock is associated with high morbidity and mortality, and its management…
Sponsor: Clinica Universidad de Navarra, Universidad de Navarra • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Laser or physio: which eases shoulder pain faster?
Symptom relief CompletedThis randomized controlled trial aimed to compare the short-term effectiveness of high-intensity laser therapy (HILT) and a multimodal physiotherapy program in patients with subacromial impingement syndrome (SIS). Ninety-four participants were allocated to either HILT or combined…
Sponsor: Tulay Yildirim • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Fall risk calculator could save lives by predicting who needs urgent care
Knowledge-focused CompletedThis retrospective, multicenter, registry-based cohort study used data from the Pan-Asian Trauma Outcomes Study registry between January 2016 and December 2024. Adult patients with fall-related trauma were included if they had available data on age, sex, emergency department vita…
Sponsor: Mackay Memorial Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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NICU staff survey reveals how End-of-Life decisions are made for newborns
Knowledge-focused CompletedIn neonatal resuscitation, the majority of deaths currently occur after a Life Limitation or Discontinuance (LAT) procedure. In the 1990s, the approach was different, as Marina CUTTINI put it in a European study that highlighted some French peculiarities: doctors and nurses found…
Sponsor: Hôpital NOVO • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC