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116076 trials found · Page 5626 of 5804
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Hip implant Check-Up: how does AMIStem hold up?
Knowledge-focused TerminatedThe purpose of this study is to evaluate radiological performance of the cementless femoral stem AMIStem H at 1 and 5-year follow-up. All the patients operated at the investigational sites between April 2009 and April 2012 will be reviewed at 1, 5 and 10 year according to standa…
Sponsor: Medacta International SA • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Study explores how race affects diabetes and heart disease risk in women
Knowledge-focused CompletedBackground: \- Rates of diabetes and heart disease in women are increasing. Early recognition of risk could help women live longer and healthier lives. Race and ethnicity may affect the best kinds of tests to use to screen for these conditions. Researchers want to compare risk f…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Laughing gas may ease pain during physio for seniors
Symptom relief CompletedThe MEOPA is used to obtain an analgesia of the short-term painful acts. To the population of elderly patients, the therapeutic resources to control the passing pain require in their manipulation a certain caution and are not divested of side effects badly tolerated at this age. …
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Stanford pays people to walk – see what happened
Knowledge-focused CompletedIn this study, the investigators will test responsiveness of young, middle-aged, and older adults to a range of incentives, some of which provide rewards for the individual participants and others that offer rewards to other people or groups. The investigators hypothesize that in…
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New breathing technique may give doctors more time during cancer screening
Knowledge-focused Completedthe aim of the study is to determine if Spontaneous Ventilation with Positive Pressure Ventilation (PPV) preoxygenation allows a longer non hypoxemic apnea time during panendoscopy compared to spontaneous breathing preoxygenation. the hypothesis is PPV extends the residual funct…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Leukemia drug dosing study aims to protect kids
Knowledge-focused Recruiting nowThis is a prospective study of children \<21 years of age with the goal of characterizing the PK of drugs administered per standard of care as prescribed by the treating caregiver.
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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French ICUs under the microscope: how safe are they really?
Knowledge-focused CompletedThe tools to measure safety culture (CS) have recently become available. No study has focused on the measure in France, apart from pilot studies. intensive services are particularly at risk of serious adverse events occurred (SAEs). Patients who are hospitalized are in fact fragi…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Heart MRI may reveal hidden danger in diabetics
Knowledge-focused TerminatedPeople with diabetes are at an increased risk of heart attacks and heart failure, and it is important to be able to treat people with diabetes who are at risk for heart disease to prevent these outcomes. This study is looking at the importance of "diffuse scar tissue" that is fou…
Phase: PHASE4 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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New CT method could slash radiation in bone scans
Knowledge-focused CompletedThe main objective of this study is to demonstrate the non-inferiority of SPECT image quality (as measured by the signal / noise ratio) obtained by ASIR reconstruction of very-low-dose CT acquisitions versus the quality of those obtained by filtered back projection (FBP) of low-d…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Which scan is better for your sinuses? new study compares CT and cone beam
Knowledge-focused CompletedThis study compares the morphological concordance between CT (computed tomography) and cone beam in sinus on 26 validated items. CT and cone beam is performed on each patient. Performances of these two imagery technics seem to be closed. Nevertheless, the exposure of the ionizing…
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Do you really know your meds? new survey tests GATTEX safety smarts
Knowledge-focused Recruiting nowThe study is about learning and documenting how well participants and physicians understand how to use GATTEX and about potential risks by using a survey (called Knowledge Assessment Survey). This survey, which is conducted every two years, is part of the Gattex Risk Evaluation a…
Sponsor: Takeda • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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Scientists use brain scans to unravel thought problems in bipolar disorder
Knowledge-focused CompletedBipolar disorder is a mental disease characterized by mood dysregulation and arises from manic, depressive or mixed episodes. The observations of the patient's speech and language behaviour due to flight of ideas or loss of goal probably result from an underlying disturbance in s…
Phase: NA • Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Mixing anesthetics may cause more blood pressure swings during breast surgery
Knowledge-focused OngoingThe purpose and the goal of this paper is to show whether the application of a combination of two local anesthetics, as opposed to the application of one local anesthetic at paravertebral block changes the hemodynamic variable. It is therefore a prospective randomized double- bli…
Phase: PHASE4 • Sponsor: University Hospital Dubrava • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Scientists investigate immune cells in Horton's disease
Knowledge-focused CompletedThe research hypothesis is that T lymphocytes CD8 play a role in the physiopathology of Horton's disease. At the inclusion visit, patients will have, as is the case in the usual strategy: * A complete clinical examination carried out by the doctor in charge of the patient * ESR…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Kids move more when they know They're being watched
Knowledge-focused CompletedEighty healthy youngsters, aged 10-18 years, will be equally randomized between the blinded and the non-blinded group. The blinded subjects will be informed that we were testing the reliability of a new device for body posture assessment and these youngsters will did not receive …
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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New registry aims to unlock mysteries of preterm membrane rupture
Knowledge-focused Recruiting nowPreterm Premature Rupture of Membranes (PPROM) before 37 weeks of pregnancy is responsible for 40% of preterm births in the United States. The PPROM Registry aims to identify possible causes of PPROM, evaluate trends in expectant management, measure maternal and fetal care, and t…
Sponsor: American Alliance for pProm Support • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Your wisdom teeth could help science: study seeks tissue samples
Knowledge-focused Recruiting nowBackground: \- The third molars (wisdom teeth) normally grow in during late adolescence or early adulthood. Many people need or choose to have these teeth removed with oral surgery. Normally, the removed teeth and tissue are thrown away as medical waste. However, oral health res…
Sponsor: National Institute of Dental and Craniofacial Research (NIDCR) • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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Hormone cream study aims to unlock pelvic floor secrets
Knowledge-focused TerminatedOur primary aim in the current study is to determine important tissue differences, including muscle and connective tissue changes, between postmenopausal women and reproductive age women with pelvic floor dysfunction to help develop targeted and noninvasive treatments.
Phase: PHASE4 • Sponsor: The University of Texas Medical Branch, Galveston • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Autism research gets a boost: new database to speed up studies
Knowledge-focused CompletedThe purpose of this study is to create a subject database to recruit for current and future studies in research on autism and other neurodevelopmental disabilities.
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Teaching parents about pain may help kids recover better after surgery
Symptom relief Recruiting nowThis study aims to assess the differences in overall pain severity, pain management, and satisfaction during recovery period between two groups of children who either receive or do not receive additional education related to expectation and management of postoperative pain.
Phase: NA • Sponsor: Columbia University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC