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116076 trials found · Page 5611 of 5804
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Scientists map immune cells in colon cancer patients
Knowledge-focused CompletedDuration of each part of the study per patient: * Screening: From 1 to 4 weeks * Sampling period (blood and tissue): 1 day * Follow-up by patient: 60 months * Total study duration by patient: 84 months * Total inclusion duration: 24 months * Total Follow-up duration: 60 months *…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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ICU recovery data: what happens after critical care?
Knowledge-focused TerminatedRegistry database of intensive care patients. These data comprises of routine data including mobilization data and follow up assessments.
Sponsor: Technical University of Munich • Aim: Knowledge-focused
Last updated Jun 26, 2026 19:04 UTC
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Which crown material is best for your molars? new study aims to find out
Knowledge-focused OngoingThis is a randomized, prospective clinical trial. The aim of the project is to assess the clinical performance of three types of tooth-supported crowns; monolithic high translucent colored zirconia, crowns of high-translucent colored zirconia with a mini-veneer buccally and crown…
Phase: NA • Sponsor: Malmö University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Researchers test if CT scan tweaks change tumor readings
Knowledge-focused OngoingThe purpose of the study is to see how measurements of tumor differences vary with slight changes in CT scan parameters. Reproducible radiomic features can be extracted for abdominal tumors, and specifically colorectal liver metastases, imaged with clinical CT scanners even in th…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Tiny study probes why islet transplants prevent low blood sugar
Knowledge-focused CompletedTo determine the effect of sympathetic neural and hormonal (epinephrine) input on islet cell hormonal responses to insulin-induced hypoglycemia in type 1 diabetic recipients of intrahepatic islet transplantation. We hypothesize that α-adrenergic (neural) blockage will abolish ins…
Phase: EARLY_PHASE1 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Newborn death prediction tool for early membrane rupture falls short
Knowledge-focused TerminatedPretern premature rupture of the membranes (PPROM) remains the leading cause of preterm deliveries and neonatal mortality and morbidity. PPROM is defined as rupture of the fetal membranes prior to 37 weeks' gestation. PPROM complicates 2-4% of all pregnancies and accounts for app…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Family videos may replace In-Person mobility tests for seniors
Knowledge-focused CompletedThe purpose of this research study is to find out if mobility (the ability to move around) can be reliably assessed by having the family or care giver caregiver take a video based test for the patient. If this study shows that mobility can be assessed by family or caregiver, this…
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Can muscle oxygen levels explain chronic back pain?
Knowledge-focused CompletedThe study evaluate paraspinal aerobic metabolism of chronic low back pain patients and healthy people during an original and standardized isokinetic protocol. The aim of this study is to determine a potential alteration of muscular aerobic metabolism in low back pain patients, i…
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Inhaler training study aims to cut COPD errors
Knowledge-focused CompletedChronic Obstructive Pulmonary Disease (COPD) is the fourth leading cause of death in the world and further increase in its prevalence and mortality has been predicted. Currently, the main long-term treatments are the long-acting beta-2 agonist, indacaterol, salmeterol and the ant…
Phase: PHASE4 • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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New sensor reads anxiety in MRI patients
Knowledge-focused CompletedThis study is to determine the possibility of assessing the level of anxiety in MRI patients by means of the respiration rate (RR) and heart rate (HR) indicators acquired by a fiber-optic sensor system. The mean RR and/or HR values recorded at the beginning and the end of an MRI …
Sponsor: Military Institute of Aviation Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Waistline may predict surgery time for rare adrenal tumor
Knowledge-focused CompletedThis retrospective observational study examines whether abdominal circumference is associated with operative time in patients undergoing retroperitoneal adrenalectomy for pheochromocytoma. Data were collected from medical records of patients treated at a single tertiary referral …
Sponsor: Asan Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Can a Pre-Surgery chat reduce pain after a nerve block?
Knowledge-focused OngoingThis is a retrospective study looking at patients who received a nerve block for surgery and assessing pain after the nerve block resolves, with or without an educational intervention, over two periods of time.
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Did hospitals follow the rules? new study examines diabetes care before, during, and after major surgery
Knowledge-focused CompletedPatients who undergo major surgery face a 15-30% risk of serious adverse events, including a 1-5% mortality risk in the first month after surgery. For patients with diabetes, the risk is even greater, and it is often aggravated by complications associated with hyper- and hypoglyc…
Sponsor: University Hospital Bispebjerg and Frederiksberg • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Dental clinic launches study to track implant success in everyday practice
Knowledge-focused Recruiting nowThis purpose of this database is to collect, store and use appropriately derived data from routine patient care in a specialist dental practice. Comprehensive observational data will be gathered, systematically organised and be continuously updated. This data will be used to eval…
Sponsor: The Campbell Clinic, UK • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Mayo clinic launches massive biobank to unlock secrets of rare liver diseases
Knowledge-focused Recruiting nowThis study is a biobank of specimens and clinical data for use in current and future research to better understand the cholestatic liver diseases primary biliary cirrhosis/cholangitis (PBC) and primary sclerosing cholangitis (PSC).
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Infants with groin opening followed for 18 years to predict hernia
Knowledge-focused OngoingThis will be a multi-center prospective observational study of all patients who undergo laparoscopic pyloromyotomy. Subjects who have PPV will be followed up to just before their 18th birthday through annual phone calls or emails to determine the incidence and timing of subsequen…
Sponsor: Children's Mercy Hospital Kansas City • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Hormone gel transfer: does washing or clothing protect women?
Knowledge-focused CompletedThis is a two-center, open-label study conducted in healthy male and female volunteers at two academic research centers. The study will consist of three single applications of the Nestorone (NES) + testosterone (T) combined gel on the shoulders/upper arms of male participants fol…
Phase: PHASE1 • Sponsor: Kimberly Myer • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Anesthesia study seeks safer surgery for heart and brain
Knowledge-focused TerminatedThe relationship between anesthetic medication and postoperative major cardiac and cerebral complications will be studied using logistic regression model.
Sponsor: Peking University First Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Timing of burn surgery: early or late? study ends early without clear answer
Knowledge-focused TerminatedThe prognostic of burn patients has improved over the last decades. Early excision of full thickness burns is thought to be one of the key factors which have led to prognostic improvement. Best timing for burn excision remain uncertain, however. In this multicenter observational …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Researchers dig into 4000 patient records to unlock esophageal cancer secrets
Knowledge-focused Recruiting nowResidual tumor at the proximal or distal margin after esophagectomy is a known prognostic factor for poor survival outcomes in patients with esophageal cancer; however, the significance of the circumferential resection margin (CRM) remains controversial. In this study, the invest…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC