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116076 trials found · Page 5598 of 5804
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Tiny study hopes to unlock why pollution hurts some lungs more
Knowledge-focused CompletedBackground: Respiratory diseases affect more than 1 billion people worldwide. They are a growing public health concern. The lungs are constantly exposed to environmental factors such as dust, fumes, microbes, and pollutants. But much is still not known about how these pollutants…
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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Simple tests may gauge fitness in seniors
Knowledge-focused CompletedA study of 64 older adults over the age of 65y to assess the utility of patient characteristics and bedside measures of physical function and muscle size to predict cardiorespiratory fitness.
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:42 UTC
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Mesh fails to prevent hernias in aortic repair patients
Knowledge-focused CompletedThe aim of the study was to compare the incidence of IH after abdominal aortic aneurysm (AAA) open repair according to the abdominal wall closure technique used. The main question it aims to answer is: Does prophylactic mesh reinforcement prevents from IH after AAA open repair? …
Sponsor: Hospital Universitario Ramon y Cajal • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Can 3D scans improve shoulder fracture diagnosis?
Knowledge-focused Recruiting nowMajority of previous classifications based on two-dimensional images to analyze these complicated 3-D fractures. Small or delicate changes in rotation and positioning can result to considerable disagreement in the interpretation of standard radiographs. Therefore, a classificatio…
Sponsor: Hebei Medical University Third Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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New gum grafting method studied in 16 patients – no treatment given
Knowledge-focused CompletedSixteen patients with horizontal deficiencies in the posterior mandible were treated with "the Open Membrane Technique" (OMT). Dense PTFE membranes covering an allograft biomaterial were used without any attempt to passivate the flap. Flap closure with an open wound (membrane exp…
Phase: NA • Sponsor: Saint-Joseph University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Running and swimming may temporarily stress kidneys, study finds
Knowledge-focused CompletedIn recent years there has been a significant increase in the number of participants in high intensity and duration sports events. This type of physical exercise has been reported to lead to an apparently transitory deterioration in kidney function. The injury mechanisms involved …
Phase: NA • Sponsor: Hospital Clínico Universitario de Valladolid • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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Could a cancer drug fix an irregular heartbeat?
Disease control CompletedGenomic studies on atrial fibrillation patients have identified polymorphisms in regions surrounding the PITX2 gene, suggesting it could be the locus responsible for atrial fibrillation. The PITX2 gene is essential for establishing the asymmetry between systemic and pulmonary blo…
Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Colonoscopy videos could help AI spot polyps better
Knowledge-focused Recruiting nowThe study shall mainly help to better evaluate the performance the APDS device and secondly it may help to assess the potential of the future alpha version of the device to be a useful and effective for the detection of colon Polyps.
Sponsor: Magentiq Eye LTD • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Kidney health may change how body handles cancer drug
Knowledge-focused CompletedThe main purpose of this study is to assess the amount of study drug that reaches the bloodstream and the time it takes for the body to get rid of it when given to participants with renal (kidney) impairment compared to healthy participants. The study will last up to 9 days, excl…
Phase: PHASE1 • Sponsor: Eli Lilly and Company • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:41 UTC
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Special lens may slow nearsightedness – tiny study looks at how
Knowledge-focused OngoingDiurnal variations in the thickness of the choroid have been reported in the literature, and, more recently, the role of the choroid has been studied with respect to its role in myopia (near-sightedness) progression.
Phase: NA • Sponsor: SightGlass Vision, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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High-Tech cameras reveal hidden walking changes in spine curvature
Knowledge-focused CompletedSpinal diseases often induce gait disorders with multifactorial origins such as lumbar pain, radicular pain, neurologic complications, or spinal deformities. However, radiography does not permit an analysis of spinal dynamics; therefore, sagittal balance dynamics during gait rema…
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Abandoned study: can a common painkiller help close a tiny heart vessel in preemies?
Disease control TerminatedThe purpose of the present study is to determine whether treatment of hemodynamically significant patent ductus arteriosus with a combined therapy of intravenous Ibuprofen and oral acetaminophen has higher success rate in closing the ductus arteriosus than a standard treatment st…
Phase: PHASE2 • Sponsor: University of South Alabama • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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Can changing What's on your plate help you eat less? new study investigates
Knowledge-focused OngoingFor weight loss to occur, energy intake needs to be reduced to incur an energy deficit. One dietary strategy that may facilitate weight loss is consuming a diet low in dietary energy density (ED). It is hypothesized that a diet low in ED, which can be achieved by a high intake of…
Phase: NA • Sponsor: The University of Tennessee, Knoxville • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Teen obesity linked to brain changes in emotional memory
Knowledge-focused TerminatedRecent studies indicate that obese teenagers exhibit memory disturbances. Adolescence represents a crucial period in the development of the hippocampus and the amygdala, necessary for the implementation of memory and emotional functions for the rest of life. Disturbances of the i…
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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New study reveals best timing for dental implants after tooth extraction
Knowledge-focused CompletedThe purpose of this study is to clinically, radiographically and histologically evaluate the healing sequence of post-extraction sockets grafted with Bio-Oss Collagen® at 3, 6 and 9 months following tooth extraction in single-rooted tooth sites. Subjects with single rooted teeth…
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Diabetes symptoms linked to balance problems in new study
Knowledge-focused CompletedThe research is a cross-sectional study and was planned to determine which diabetes mellitus symptoms related to physical competence have a greater impact on balance in patients with diabetes mellitus
Sponsor: Suleyman Demirel University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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New tool helps patients and doctors choose psoriasis treatments together
Knowledge-focused CompletedThe purpose of this study is to create and test a patient decision aid that facilitates the shared decision-making process when patients with psoriasis and/or psoriatic arthritis are starting or switching to a new therapy.
Phase: NA • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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New slip machine reveals balance secrets in spinal injury patients
Knowledge-focused OngoingThe objective of this project is to fully test a newly developed affordable cost variable slip inducer in the ambulatory, incomplete spinal cord population. It is a self-contained device using a moving serial plank mechanism with wheels on the underside of each plank that allow f…
Phase: NA • Sponsor: Shirley Ryan AbilityLab • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Tiny study on nerve stimulation for pain halted early
Knowledge-focused TerminatedThe goal is to document efficacy of PF-SCS therapy in a blinded fashion and better understand how SCS therapy works in the clinical setting. Overall the investigators hope to improve patient care and selection of candidates who have the best potential for effective pain relief fr…
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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New study sheds light on swallowing issues in brain injury patients
Knowledge-focused CompletedThis study aimed to characterize swallowing disorders in minimally consciousness patients after brain traumatic injury.
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC