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116076 trials found · Page 5560 of 5804
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Early antibiotics in ICU aspiration: small trial halted before answers
Disease control TerminatedThe purpose of this study is to evaluate the use of early antibiotics in ICU patients who appear to have aspirated, to help determine whether this improves outcomes by reducing the later incidence of pneumonia and other negative consequences.
Phase: PHASE4 • Sponsor: UConn Health • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Spinal vs. general anesthesia: which causes less inflammation in hernia repair?
Knowledge-focused CompletedObjective: This study aimed to compare the effects of general and spinal anesthesia on the inflammatory response by measuring intercellular adhesion molecule-1 (ICAM-1), P-selectin (SELP), and thrombomodulin (TM) levels in patients undergoing inguinal hernia repair. Materials a…
Phase: NA • Sponsor: Sezen Kumaş Solak • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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New diabetes drug candidate passes first safety check in healthy volunteers
Knowledge-focused CompletedThe objective of the study is to assess the safety, tolerability and pharmacokinetics of HR011408 at two formulations in healthy subject.
Phase: PHASE1 • Sponsor: Jiangsu HengRui Medicine Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Quick stool test device could cut isolation time for cancer patients
Knowledge-focused Completedstool sample device tested on patients admitted to oncological dept. with diarrhea, in order to shorten time in isolation and time to relevant treatment.
Phase: NA • Sponsor: Zealand University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Are heart patients moving enough? new study investigates
Knowledge-focused CompletedPhysical activity is defined as any bodily movement that results in energy expenditure. Athletes are individuals who engage in planned, structured physical exercise under guidance, with specific goals and competitive objectives. For this population, pre-participation cardiovascul…
Sponsor: University of Sao Paulo • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:25 UTC
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New algorithm could help ERs decide who really needs to stay
Knowledge-focused OngoingThe aim of this study is to develop, study and validate a rigorous and sustainable method for assessing the clinical appropriateness of the decision taken in the Emergency Department to admit or not to admit patients.
Sponsor: Mario Negri Institute for Pharmacological Research • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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CrossFit injury watch: island study reveals how athletes get hurt
Knowledge-focused TerminatedThis study aims to precisely describe epidemiology of injuries than occur during practice of crossfit. Each participant will complete questionnaires in order to identify injuries. The first questionnaire will be completed at the moment of the inclusion and the second questionnair…
Sponsor: Centre Hospitalier Universitaire de la Réunion • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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New registry aims to unlock secrets of rare liver cancer
Knowledge-focused CompletedThe purpose of this study is to collect information about people with fibrolamellar cancer (FLC). This study is a registry of people with FLC around the world. This study will involve collecting information about participants, their medical history and the regular medical care th…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Skip the treadmill? new study tests a quicker way to gauge surgical fitness
Knowledge-focused Recruiting nowThis study will compare the measured oxygen consumption (VO2) obtained during sub-maximal exercise testing with the estimated VO2 derived from a non-exercise questionnaire.
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Polish breast cancer treatment patterns revealed in new study
Knowledge-focused CompletedThe study is descriptive and aims to characterize the treatment patterns of advanced breast cancer in Poland in the real-world data setting. The main goals are to assess the current treatment patterns of hormone receptor-positive (HR+) Human epidermal growth factor receptor 2 neg…
Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Scientists track breast milk changes in 769 chinese moms
Knowledge-focused CompletedThis is a cohort study to understand the changes of breastmilk composition in the first six months after birth of Chinese infants.
Sponsor: Danone Nutricia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Bladder cancer biobank aims to fuel future discoveries
Knowledge-focused Recruiting nowThe goal of this study is to collect tumor samples, urines, stool and blood from patients with urothelial carcinoma. These samples will be stored in a secure and confidential laboratory of the Toulouse University Hospital.
Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Tiny study checks if COVID-19 spreads during surgery
Knowledge-focused CompletedSars-Cov2 has been found in the digestive tract, as well as the respiratory tract. Protection of health care workers during surgery has been increased and some guidelines advocate for abandoning laparoscopy in COVID19 patients for fear of contamination, evenghtough this does not …
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Opioid blocker may reveal Brain's social secrets
Knowledge-focused Recruiting nowThe study is a randomized, placebo-controlled design with the opioid antagonist, oral naltrexone. Following random assignment, participants will take 50mg of naltrexone or placebo once a day for 7 days. On days 1 - 7, participants complete reports of their feelings of social conn…
Phase: EARLY_PHASE1 • Sponsor: San Diego State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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New MRI study aims to make scans faster and better for all organs
Knowledge-focused Recruiting nowCross-sectional observational study to improve MRI data acquisition techniques by optimising MRI sequences for multiple organs and assessing the repeatability and reproducibility of multiparametric MRI, in healthy volunteers.
Sponsor: Perspectum • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Reach and train: a High-Tech balance test for stroke recovery
Knowledge-focused CompletedThis is a proposal to develop a Balanced Reach Training Protocol (BRTP) to evaluate and train dynamic standing balance. The BRTP is based upon the Balanced Reach Test (BRT) that the investigators previously developed and validated. In the BRT subjects stand and point to a target …
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Preworkout supplement may boost tired muscles, small study suggests
Knowledge-focused CompletedThe primary purpose of the present study was to examine the acute effects of a MIPS product on peak torque production of the leg extensors during a fatiguing isokinetic protocol involving isometric, concentric, and eccentric muscle actions. In addition, we investigated the effect…
Phase: NA • Sponsor: Northern Illinois University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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New daily contact lenses put to the comfort test
Symptom relief CompletedThe purpose of this study is to assess the wear experience of existing wearers of a monthly replacement contact lens after they have been fit with a daily disposable contact lens that has water surface treatment.
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Beet juice shows promise for heart and lung health in small study
Knowledge-focused CompletedOlder adults with coronary artery disease (CAD) have impaired vascular and inspiratory muscle function. The overarching goal of this double-blind, randomized, crossover, placebo-controlled pilot trial was to inform the development of a fully powered trial to evaluate the effects …
Phase: NA • Sponsor: University of Florida • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Standing wheelchairs for kids: a tiny study hopes to open doors
Knowledge-focused OngoingFor children who use a power wheelchair, a powered wheelchair standing device (PWSD) may be considered for daily use. A PWSD allows a child to electronically move between sitting and standing and can be driven in either position. Existing published PWSD research in pediatrics is …
Phase: NA • Sponsor: Grand Valley State University • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:22 UTC