Nasal spray could replace needles for Pre-Surgery anxiety in toddlers
NCT ID NCT03725930
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a clonidine nasal spray can calm young children (ages 1-5) before minor surgery. Researchers compared it to a placebo spray in 90 kids. The goal was to see if the spray reduces anxiety and helps children accept the anesthesia mask more easily.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- clonidine nasal spray
- What this could lead to
- If it works, this could provide a needle-free way to reduce anxiety in young children before surgery.
- What could go wrong
- This is a small, completed Phase 3 trial with only 90 participants, so results may not apply to all children. Clonidine can cause side effects like low blood pressure or drowsiness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
CHRU Lille
Lille, Nord, 59000, France
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