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116076 trials found · Page 5551 of 5804
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Sugar-Tweaked heart hormone tested in healthy volunteers
Knowledge-focused CompletedThe human heart produces hormones that help regulate blood pressure and fluid balance in the body. One of these hormones is atrial natriuretic peptide (ANP). ANP lowers blood pressure by relaxing blood vessels and increasing urinary excretion by the kidneys. Previous research ha…
Phase: EARLY_PHASE1 • Sponsor: Peter Fruergaard Andersen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Weight matters: study links BMI to anesthesia drug needs
Knowledge-focused CompletedThis single-center prospective observational study investigates the effect of body mass index (BMI) on intraoperative vasopressor requirements and spinal block characteristics in adult patients undergoing urological surgery under spinal anesthesia. Participants are classified int…
Sponsor: Adiyaman University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Small study compares standard vs mini kidney stone surgery
Knowledge-focused CompletedRandomized comparison of patient outcomes following standard PCNL versus mini-PCNL.
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Can fitness help kids process fatty foods? small study explores link
Knowledge-focused CompletedThe objective is to determine if how physical fitness, measured using a treadmill maximal oxidative capacity test, is associated with the capacity to metabolize a high-fat meal in pediatrics (ages 8-17 years). Ability to metabolize the meal will be assessed by profiling mitochond…
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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White bread vs wholemeal: does body weight affect blood sugar spikes?
Knowledge-focused CompletedObesity and increased blood glucose peaks are risk factors for type 2 diabetes mellitus (T2DM). Few studies have explored whether increased body fat contributes to higher blood glucose peaks after food consumption. This study aimed to investigate differences in blood glucose lev…
Phase: NA • Sponsor: City, University of London • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:08 UTC
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200 patient records reviewed to check safety of artery repair patch
Knowledge-focused CompletedUni-Graft® K DV Patch is marketed in Europe since 1999 for reconstructive interventions of the deep femoral, femoral and iliac artery and was also indicated for carotid interventions until 01/2020. Previous studies focused on the clinical performance of different patch materials …
Sponsor: Aesculap AG • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Herbal injections for pain: are they safe? large study investigates
Knowledge-focused CompletedThe purpose of this study is to evaluate the safety of pharmacopuncture by observing any adverse events that may occur after pharmacopuncture treatment in with spinal joint disease hospitalized patients at 7 Korean medicine hospitals and analyzing blood test results.
Sponsor: Jaseng Medical Foundation • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:46 UTC
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Teens with higher BMI may face more gum trouble during braces treatment
Knowledge-focused Recruiting nowThe goal of this prospective observational study is to assess the influence of increased body mass index (BMI) on various oral health and orthodontic-related parameters in adolescents undergoing orthodontic therapy (OT) with braces. These parameters include gum inflammation, toot…
Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Brain chemistry study explores attention in aging
Knowledge-focused CompletedThis study will use an anticholinergic pharmacological probe to examine attention network function in SCD using EEG. The overall hypothesis is that in older adults with SCD, normal cognitive performance is maintained by compensatory attention network activity, supported by enhanc…
Phase: EARLY_PHASE1 • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:28 UTC
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Pedal power: 8-Week training trick may give young cyclists an edge
Symptom relief CompletedAbstract Purpose: The objective of this study is to assess the influence of pedal technique development training regimen on functional threshold power, lower extremity knee isokinetic power, and right-left knee power ratio differences. Methods: Twenty-three male athletes with an…
Phase: NA • Sponsor: Istanbul Topkapi University • Aim: Symptom relief
Last updated Jun 26, 2026 15:23 UTC
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New tool aims to help melanoma patients with autoimmune conditions navigate treatment decisions
Knowledge-focused Recruiting nowThis study learn how easily patients can use an educational tool that will be created for patients with melanoma and pre-existing autoimmune diseases who receive or will receive immune checkpoint inhibitor drugs. Patients will be asked their opinions about the design, accessibili…
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Study reveals how many patients suffer chronic pain after sternotomy
Knowledge-focused CompletedChronic postoperative pain is a well-known problem. Chronic postoperative pain is defined as pain that begins following a surgical procedure and persists for more than 2 months without other obvious causes such as infection or underlying disease. Sternotomy causes significant pos…
Sponsor: Ankara City Hospital Bilkent • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Tiny study peers inside the brain during autism therapy
Knowledge-focused CompletedThis pilot study aims to identify behavioral and neural measures of sensory processing and attention associated with routine occupational therapy intervention for children with autism spectrum disorders. Specifically, the investigator will examine the impact of a child's level of…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Cholesterol drug studied as abortion pill alternative
Disease control CompletedMedication abortion is a way of ending a pregnancy using pills. The current FDA-approved regimen for medication abortion uses mifepristone and misoprostol. This study is testing whether a different medication, atorvastatin, followed by misoprostol, can be used to end a pregnancy.…
Phase: EARLY_PHASE1 • Sponsor: University of Utah • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New diabetes drug tested in patients with liver issues
Knowledge-focused CompletedTo evaluate the pharmacokinetic characteristics of pyroglutamate rongliflozin capsules in subjects with mild and moderate liver damage and healthy subjects
Phase: PHASE1 • Sponsor: Sunshine Lake Pharma Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Researchers investigate Cortisol's role in rare fat disorder
Knowledge-focused CompletedFamilial partial lipodystrophic syndromes are characterized by an increase in visceral adipose tissue and an atrophy of subcutaneous adipose tissue. They are associated with a severe metabolic syndrome especially when linked to the mutation of the R482 codon of the LMNA gene (Fam…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Sound waves shed light on nerve and muscle health
Knowledge-focused Recruiting nowBackground: Current techniques used to measure the health and function of a person s nerves and muscles are generally effective, but they do have limits. Researchers are looking for ways to improve the ability to observe nerves and muscles and how they function in this natural h…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Could a vaccine shot into warts make them disappear?
Disease control CompletedThis study will investigate whether injecting genital warts with small quantities of the Gardasil 9 vaccine has an effect on the warts.
Phase: PHASE1, PHASE2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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New study reveals how sugammadex works in obese patients during surgery
Knowledge-focused CompletedThe purpose of this study is to illustrate pharmacokinetics of sugammadex in reversal of vecuronium-induced neuromuscular blockade in patients during laparoscopic surgery
Phase: PHASE4 • Sponsor: Guangzhou General Hospital of Guangzhou Military Command • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC
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Can pictures of smells cure motion sickness in virtual reality?
Knowledge-focused CompletedThe aim of this study is to, using fMRI, compare brain activations during olfactory imagery induced by different visual supports (words, pictures, colors and colored arrangements) in healthy subjects. This will allow us to choose the best olfactory imagery facilitator and to ass…
Phase: NA • Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC