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127005 trials found · Page 5348 of 6351
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New study tests if video laryngoscopy makes tracheostomy safer
Knowledge-focused Recruiting nowWhen preparing an ICU patient for percutaneous dilational tracheostomy, correct positioning of the endotracheal tube is important. During the procedure, it is possible to puncture the cuff. Tracheal tube cuff puncture can lead to failure of ventilation, loss of positive end-expir…
Sponsor: Hospital Clinico Universitario de Santiago • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:24 UTC
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Therapy dogs may ease Kids' fear of needles and dentists
Symptom relief Recruiting nowThe purpose of the present study is to evaluate the efficacy of Animal Assisted Therapy (AAT) during blood extraction or dental procedures in a Primary Care Pediatric Service. Determine the improvement in facilitating the task of venipuncture or dental extraction for nursing or d…
Sponsor: Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina • Aim: Symptom relief
Last updated Jun 26, 2026 16:59 UTC
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Does anesthesia flow rate affect inflammation in obesity surgery?
Knowledge-focused CompletedThis retrospective observational study aimed to compare the effects of low-flow and standard-flow sevoflurane anesthesia on perioperative inflammatory responses in patients undergoing laparoscopic sleeve gastrectomy for obesity. Data were obtained from the anesthesia and laborato…
Sponsor: Adana City Training and Research Hospital • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC
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Simple exercises may strengthen back muscles in teens with curved spine
Symptom relief CompletedThe study population comprised patients with AIS who had applied to the outpatient clinic between January and June 2022. The patients were divided into two groups. Treatment group(TG) was instructed in specific scoliosis exercises, while the Control group(CG) was given exercises …
Sponsor: Sisli Hamidiye Etfal Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Could a simple Add-On drug make C-Section recovery smoother?
Symptom relief CompletedThe study hypothesizes that addition of dexmedetomidine to bupivacaine either in spinal anesthesia or TAP block is more effective and provide better ObsQor-11score than bupivacaine alone. Also, Dexmedetomidine in TAP block might provide a longer pain free time in comparison to in…
Phase 4 • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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Thymus surgery outcomes: what predicts success in myasthenia gravis?
Knowledge-focused CompletedThis study aimed to assess and compare predictors of outcome in patients with thymomatous and non-thymomatous MG undergoing Thoracoscopic thymectomy.
Sponsor: Tanta University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Neck pain relief: do added numbing drugs help?
Symptom relief CompletedThis study aims to evaluate the efficacy of local anesthetic drugs in cervical epidural injections for chronic neck pain.
Sponsor: Mustafa Kurçaloğlu • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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New registry aims to improve bile duct stone removal
Knowledge-focused OngoingThe Percutaneous Cholangiopancreatoscopy (PCPS) registry is an observational, multicentric, prospective, and retrospective registry of patients undergoing the percutaneous cholangiopancreatoscopy procedure at sites across the United States. In the retrospective component of the s…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Blood test scores may reveal heart attack risk
Knowledge-focused CompletedIt is well known that malnutrition is a prognostic risk factor in chronic heart failure (CHF). Weight loss and the development of cardiac cachexia are associated with poor prognosis in CHF. However, objective indices such as the Prognostic Nutrition Index (PNI) and Controlling Nu…
Sponsor: Muğla Sıtkı Koçman University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Brain waves may reveal who will feel more pain after root canal
Knowledge-focused CompletedThis observational study evaluates whether resting-state EEG alpha activity can help identify endodontic patients at higher risk of post-operative pain following single-visit root canal treatment. EEG will be recorded before treatment and pain intensity will be self-reported usin…
Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Spinal tumor surgery under the microscope: what really happens?
Knowledge-focused OngoingIntradurale spinal tumors are rare neoplastic lesions that involve the spinal cord and surrounding structures and may cause neurological symptoms such as pain, motor deficits, sensory disturbances, and sphincter dysfunction. Surgical resection is often the primary treatment when …
Sponsor: Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Blood test may reveal hidden inflammation in back pain patients
Knowledge-focused CompletedThis retrospective cross-sectional observational study aims to evaluate the association between the C-reactive protein-albumin-lymphocyte (CALLY) index and disease activity and functional status in patients with ankylosing spondylitis. Medical records of adult patients followed b…
Sponsor: Bursa City Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Shock therapy vs. pills: which depression treatment wins on cost?
Knowledge-focused OngoingProspective observational cohort study to determine cost-effectiveness of ECT compared to medication in the treatment of major depressive disorder (MDD) in the Netherlands.
Sponsor: Radboud University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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ER wait after admission costs millions, study finds
Knowledge-focused CompletedThe goal of this observational study is to learn about the risk factors, costs, and operational impacts of emergency department boarding (patients admitted to the hospital but remaining in the emergency department awaiting placement on an inpatient floor) The main questions it a…
Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Robot suit training may ease bowel problems in spinal cord injury
Symptom relief CompletedThe purpose of the study is to assess the effects of exoskeleton training on neurogenic bowel disorders in spinal cord injury/ disease.
Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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5,000 ICU patients to help unlock secrets of critical illness
Knowledge-focused Recruiting nowRationale: There is large heterogeneity in disease states of critically ill patients at ICU admittance and there is also large heterogeneity in their disease severity during ICU stay. Still, some patients may show remarkable similarities in disease patterns. There is a lack of un…
Sponsor: University Medical Center Groningen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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AI model could spot hidden blood clot risk in ICU patients
Knowledge-focused CompletedVenous thromboembolism remains a leading cause of preventable mortality in intensive care unit (ICU) patients. Existing risk-stratification tools were developed in general medical populations and lack ICU-specific predictors. This study was to develop and validate an interpretabl…
Sponsor: Beijing Tsinghua Chang Gung Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Skip the tacks? study tests Pain-Free hernia repair
Symptom relief CompletedThe role of mesh fixation in laparoscopic totally extraperitoneal (TEP) inguinal hernia repair remains controversial. While fixation may increase postoperative pain, concerns about recurrence in larger defects prevent its complete abandonment. This study aimed to compare absorbab…
Sponsor: Antalya Health Sciences University • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Could a simple blood test spot eye damage from diabetes?
Knowledge-focused Recruiting nowDiabetic retinopathy (DR) is a complication of diabetes in which blood vessels supplying blood to the back of the eye (retina) are dysfunctional. This can lead to an improper supply of oxygen and nutrients to the retinal tissue, or it may trigger the formation of new blood vessel…
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jul 25, 2026 00:00 UTC
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Lung disease mystery: 1500 patients to be tracked for clues
Knowledge-focused CompletedThe purpose of the study is to conduct a descriptive analysis of the population of patients with an interstitial lung disease received in the pulmonary department of University hospital of Nice (France). Analysis and documentation of clinical forms of the disease, therapeutics us…
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC