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The primary purpose of this study is to evaluate the effect of mitapivat on albumin creatinine ratio (ACR) response in participants with sickle cell disease (SCD) and nephropathy.

The main purpse of this study is to evaluate the safety and tolerability of KSD-101 in patients with advanced clear cell renal cell carcinoma, to evaluate the initial clinical outcomes , immune response, and to evaluate the impact of KSD-201 on the quality of life in patients wit…

Health awareness videos are integral in disseminating knowledge about respiratory infectious diseases (RIDs). The aim of this study is to produce and evaluate an evidence-based health awareness video on precautionary measures against respiratory infectious diseases among public t…

Recent studies have highlighted the comparative advantages of perineural dexamethasone, particularly regarding its safety profile and its ability to prolong analgesia in various peripheral nerve blocks. A recent systematic review demonstrated that perineural administration of dex…

The purpose of this clinical trial is to use the medical magnetic resonance imaging system MR 7700 to perform phosphorus (31P) and sodium (23Na) scanning imaging on the human body, evaluate the image quality of phosphorus (31P) and sodium (23Na) scanning, as well as the machine c…

This study investigates the effects of moderate physical exercise and cyclic sighing (breathing training) on stress, cognition, and physiological markers in young adults. It is a randomized cross-over trial with two interventions. Each participant will take part in two interventi…

The purpose of this study is to develop the Turkish version of the CTS-6 Evaluation Tool and to comprehensively assess its validity and reliability in the Turkish population. The CTS-6 Evaluation Tool is a widely used and reliable instrument for the assessment of diagnosis and sy…

This study aims to evaluate the level of knowledge regarding periodontal disease and its association with periodontal health status among health sciences students. An observational, cross-sectional, analytical, and comparative design will be conducted involving two cohorts: final…

This study has two main objectives: First, to better understand how a motor task commonly used by researchers, known as the Fitts' task, is performed in virtual reality. It consists of reaching a target, which may be large or small, by extending the right arm. This task is simila…

Constipation is a common problem in children with cerebral palsy and may negatively affect daily activities, quality of life, and family well-being. Several factors such as nutrition, physical activity level, functional status, and psychological condition of the caregiver may be …

A significant proportion of patients hospitalized in intensive care units (ICUs) require mechanical ventilation, and the treatments applied during this process may cause pain. Pain is defined as an unpleasant sensory and emotional experience associated with actual or potential ti…

The aim of this study is to examine, using a comparative and experimental approach, the effects of nomophobia (fear of being without a smartphone) levels on acute neuromuscular and cognitive fatigue susceptibility induced by a standard physical exertion in young adults.

Since the 2021 revision of French bioethics laws, access to assisted reproductive technologies (ART) has expanded, leading to a significant increase in gamete donation requests. In this context, oocyte donation remains a limited resource, with marked disparities between centers a…

The Impact of Health Literacy on the Attitudes toward Pharmacological Treatment in Patients with Schizophrenia Spectrum Disorder This interventional study is aimed at: * assessing and improving the health literacy and * assessing the attitude towards treatment of patients with …

This study aims to explore the relationships between knowledge about pain, coping strategies, and sexual function in adults with chronic pelvic pain. Chronic pelvic pain is a persistent condition that can affect physical health, emotional wellbeing, and daily life. Research sugge…

The goal of this observational study is to learn more about the relationship between the size and shape of the eye and the shape of the face in healthy young adults. In particular, the study focuses on whether specific eye measurements are linked to certain facial characteristics…

This study adopts a non-randomized, open label, parallel, single-dose design to evaluate the safety and pharmacokinetic characteristics of Buagafuran capsules in participants with hepatic impairment.

The objective of this cross-sectional study is to explore the multi-dimensional factors influencing the shift toward "Ego-Tucking" (Fo-xi) mindsets among the contemporary student population. By utilizing a comprehensive structured questionnaire, the research aims to quantify how …

The existing literature demonstrates that motor learning strategies are effective in enhancing sports performance. One of these strategies, augmented feedback, is widely used in athletic training to help athletes achieve their goals more effectively, support the learning process,…

This is an investigator-initiated, international, multicenter, prospective, cross-sectional study that aims to 1) describe the incidence and types of postoperative pulmonary complications (PPCs), 2) describe patient demographics, baseline characteristics, and intraoperative venti…