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116076 trials found · Page 5127 of 5804
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Could a simple shot replace IV drips for nausea?
Symptom relief CompletedSubcutaneous (SC) route has become a standard of care of many drugs administration in palliative medicine. A preliminary study showed that, although it was widely adopted among palliative care practitioners for routinely prescribed medications, standards of proof are still lackin…
Phase: PHASE3 • Sponsor: University Hospital, Bordeaux • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Heart imaging study aims to predict cardiac events
Knowledge-focused Recruiting nowThe purpose of this study is to evaluate the prognosis of coronary stenosis based on intracoronary Imaging.
Sponsor: Seung-Jung Park • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Heart attack stents face off: which heals better?
Knowledge-focused CompletedTo assess strut coverage in patients presenting an acute myocardial infarction and treated either with the SYNERGY stent or the Bioresorbable Vascular Scaffold, through a parallel group design.
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Rare, deadly skin condition under the microscope: french study sheds light on calciphylaxis
Knowledge-focused CompletedCalciphylaxis, also called Calcific Uremic Arteriolopathy (CUA) is a lethal affection mostly affecting patient in end stage renal disease. The survival rate is described around 20 to 46% at one year. Clinical presentation is very painful skin lesions with ulceration mostly locat…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Scientists probe epigenetic secrets behind apple and pear body shapes
Knowledge-focused OngoingThe purpose of this study is to collect data to help researchers better understand the different ways that women or men store fat (apple shape versus pear shape).
Phase: NA • Sponsor: AdventHealth Translational Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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New eye scanner software could sharpen diagnosis of macular degeneration
Diagnosis TerminatedThe purpose of this study is to evaluate this AngioScan angiography software on patients with various retinal vascular disorders. The advanced OCT instrument is an FDA approved clinically used camera, but the AngioScan angiography software is not FDA approved. Investigators would…
Sponsor: University of California, Los Angeles • Aim: Diagnosis
Last updated Jun 27, 2026 12:10 UTC
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Simple home workouts may boost strength before liver transplant
Symptom relief CompletedPhysical exercise has been identified as a major beneficial factor in the management of patients suffering from many chronic diseases especially cancer and in the context of cardiac or pulmonary transplantation. It contributes to an improvement of the quality of life and decrease…
Phase: NA • Sponsor: University Hospital, Limoges • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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Massive study tracks 31,000 people to uncover heart risks from obesity and hypertension
Knowledge-focused OngoingLong-term Impact of Overweight/Obesity and Hypertension on Cardiovascular Risk in Middle-aged and Elderly Adults
Sponsor: Beijing Friendship Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Massive biobank aims to unlock secrets of down syndrome
Knowledge-focused Recruiting nowThe Human Trisome Project will significantly increase the speed of Down syndrome research and the understanding of associated medical conditions. Its biobank will provide de-identified samples to research.
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Massive study tracks fatty liver disease patients to uncover Real-World treatment patterns
Knowledge-focused CompletedTARGET-NASH is a longitudinal observational cohort study of patients being managed for NASH and related conditions across the entire spectrum NAFLD in usual clinical practice. TARGET-NASH is a research registry of patients with NAFL or NASH within academic and community real-worl…
Sponsor: Target PharmaSolutions, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Study measures stress of genetic testing in breast cancer patients
Knowledge-focused OngoingThis prospective Medical College of Wisconsin Cancer Center study will evaluate stress levels in breast cancer patients undergoing genetic testing. It aims to establish baseline stress levels, evaluate pre- and post-test stress levels at multiple time points, focus on the changes…
Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Preterm Kids' reading skills may get boost from early language training
Knowledge-focused TerminatedA total of 40% of neurodevelopmental difficulties have been reported in very premature infants less than 32 weeks of age. The Epipage1 study reported a decreasing prevalence of cerebral palsy (9-6%) but a high prevalence of specific cognitive neurological difficulties and an incr…
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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New study aims to predict prostate cancer treatment success using blood and scans
Knowledge-focused Recruiting nowThe purpose of this research study is to learn about: 1) How standard radiation treatment to prostate (primary radiotherapy) or the pelvis after prostatectomy (postoperative radiotherapy) may cause changes in MRI and PET imaging traits that might be used in the future to predict …
Sponsor: University of Miami • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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New imaging strategy after heart valve procedure shows promise in pilot study
Knowledge-focused CompletedEvaluation of a strategy of selected revascularization guided on myocardial ischemia detection after the TAVI procedure by using single photon emission computed tomography (SPECT) myocardial perfusion imaging.
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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New 3D X-Ray technique could replace MRI for salivary gland diagnosis
Diagnosis CompletedNon tumor salivary gland diseases are common and include sialadenitis, sialadenosis, stones, stricture and ductal dilatation, anatomical abnormalities. A radiological examination is required in order to sign the diagnosis, locate precisely the lesions and define the therapeutic s…
Sponsor: Nantes University Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 14:02 UTC
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New tool aims to give voice to oral health struggles in schizophrenia
Knowledge-focused CompletedApart from objective criteria for the evaluation of oral health (CAO, CPI…), there are no scales to evaluate the oral health of patients with schizophrenia. The only scales that do exist are for the population at large, children or the elderly. Given the severely deteriorated ora…
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Massive gene hunt aims to unlock secrets of blood disorders
Knowledge-focused Recruiting nowThe purpose of this study is to collect and store samples and health information for current and future research to learn more about the causes and treatment of blood diseases. This is not a therapeutic or diagnostic protocol for clinical purposes. Blood, bone marrow, hair follic…
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Blood pressure drug riociguat tested for Long-Term use in rare lung condition
Disease control CompletedTo provide riociguat therapy to eligible patients with PAH originating from Bayer-sponsored trials with BAY63-2521/ Riociguat / Adempas® who are currently or recently treated in these trials until lack of patient benefit as assessed by investigator, or commercial availability and…
Phase: PHASE4 • Sponsor: Bayer • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Massive study to unravel genetic mysteries of aortic disease
Knowledge-focused Recruiting nowThe Montalcino Aortic Consortium (MAC) will provide the infrastructure to assemble large cohorts of patients with mutations in known heritable thoracic aortic disease (H-TAD) genes, define the phenotype associated with these genes, and determine genetic and environmental modifier…
Sponsor: The University of Texas Health Science Center, Houston • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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2000-Patient study aims to predict heart risks from leaky valve
Knowledge-focused Recruiting nowMitral regurgitation (MR) is a common valvular heart disease worldwide, and untreated severe MR is associated with an elevated risk of heart failure and mortality. According to causes, MR could be divided into primary or secondary MR. The risk factors of mortality or heart failur…
Sponsor: Sun Yat-sen University • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:34 UTC