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116076 trials found · Page 4958 of 5804
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Sleep struggles in blistering skin disease: new study investigates
Knowledge-focused CompletedBullous pemphigoid (BP) is the most common autoimmune blistering disorder. The incidence of BP has increased due to increased life expectancy, particularly in developed countries, which can be associated with multiple geriatric comorbidities and polypharmacy. Epidemiological stu…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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5,000 patients join Yale's quest to crack rheumatic disease mysteries
Knowledge-focused Recruiting nowTo facilitate clinical, basic science, and translational research projects involving the study of rheumatic diseases.
Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Scientists probe immune cells in kids with sepsis to prevent organ injury
Knowledge-focused Recruiting nowIn this research study we want to learn more about the character of neutrophils that are present in the blood of children with sepsis. Sepsis is a severe type of infection, affecting various parts of the body. Neutrophils are a type of white blood cell that are part of the body's…
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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COVID-19 in pregnancy: new study probes placenta for clues
Knowledge-focused CompletedLittle is known regarding the effect of antenatal COVID-19 on pregnancy outcomes. The purpose of this study is to determine of COVID-19 alters histopathology and gene expression of the placenta, as evidenced by analysis at time of delivery. The analysis will aim to identify wheth…
Sponsor: Prisma Health-Upstate • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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New device may predict recovery after nerve surgery
Knowledge-focused CompletedThe study will be a non-blinded two cohort design consisting only of symptomatic patients with CuTS or compressive peroneal neuropathy or in need of peroneal nerve decompression. The first cohort will be - patients with CuTS. Evaluation of each CuTS patient will include assessmen…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:52 UTC
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New study unlocks secrets of language learning in kids with DLD
Knowledge-focused CompletedThis broad aim of this clinical study is to assess the hypothesis that morphological and phonological deficits are linked by a broader deficit in sequential pattern learning. This hypothesis applies to learning in general, but is especially critical as an avenue for developing ea…
Phase: NA • Sponsor: Father Flanagan's Boys' Home • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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New study explores language learning in kids with DLD
Knowledge-focused CompletedThis broad aim of this clinical study is to assess the hypothesis that morphological and phonological deficits are linked by a broader deficit in sequential pattern learning. This hypothesis applies to learning in general, but is especially critical as an avenue for developing ea…
Phase: NA • Sponsor: Father Flanagan's Boys' Home • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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New MRI technique could reveal how well IPF treatments really work
Knowledge-focused OngoingThe purpose of this study is being done to determine whether magnetic resonance imaging (MRI) using inhaled hyper-polarized 129 Xenon gas can help visualize impaired lung function to detect changes over time in Idiopathic Pulmonary Fibrosis (IPF) patients receiving approved IPF t…
Phase: PHASE2 • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Can learning to relax help Parkinson's patients and their caregivers?
Symptom relief CompletedSMART-PD is an 8-session program designed to decrease the physiological, emotional, cognitive and behavioral effects of stress in participants with Parkinson's disease and their caregivers by teaching cognitive-behavioral techniques and relaxation skills to help participants lear…
Phase: NA • Sponsor: Stony Brook University • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Can a video chat program ease the burden of chronic GVHD?
Symptom relief OngoingThis research is being done to evaluate the feasibility and efficacy of a multidisciplinary, patient-centered intervention, Horizons Program, versus minimally enhanced standard care to improve quality of life, symptom burden and psychological distress of adults who received an al…
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Experimental cancer drug study halted early
Disease control TerminatedThe purpose of this study is to evaluate the safety, tolerability, and preliminary activity of SQ3370 in patients with advanced solid tumors.
Phase: PHASE1, PHASE2 • Sponsor: Shasqi, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Can a device alert predict heart failure worsening?
Knowledge-focused OngoingMedtronic is sponsoring the HFRS PAS to evaluate the HFRS feature (TriageHF) when used in routine clinical practice following commercial release. The HFRS PAS is conducted within Medtronic's Product Surveillance Registry (PSR) platform.
Sponsor: Medtronic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Massive HS study aims to unlock secrets of debilitating skin disease
Knowledge-focused Recruiting nowHidradenitis suppurativa (HS) is a common and debilitating skin disease that is poorly understood and understudied. As a result, little is known about disease prognosis and few effective treatments exist for this condition. This prospective observational cohort study aims to comp…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Knee replacement recovery gets a tech boost: apps aim to get patients moving
Symptom relief CompletedThe purpose of this study is to examine the effects of two technology interventions on health outcomes (e.g., physical activity, sedentary behavior, physical function, pain) after knee replacement at 2 and 5 months .
Phase: NA • Sponsor: University of South Carolina • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Which radiation is safer for the heart? new study compares proton and photon therapy in breast cancer patients.
Knowledge-focused CompletedThis is a companion study to the "Pragmatic Randomized Trial of Proton vs Photon Therapy for Patients with non-Metastatic Breast Cancer Receiving Comprehensive Nodal Radiation: A Radiotherapy Comparative Effectiveness (RadComp) Consortium Trial" (NCT02603341). The investigators w…
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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New MRI coil could revolutionize heart attack imaging
Knowledge-focused Recruiting nowThe main aim of the study is to build and test a cardiac-specific coil purposely assembled in house to suit the FFC-MRI whole-body prototype and to test if it could be used for clinical cardiac scans in human subject populations.
Phase: NA • Sponsor: University of Aberdeen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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Ancient remedy takes on chemo nerve damage
Symptom relief CompletedThis study aims to evaluate the efficacy and safety of Roasted Nux Vomica Capsules in the treatment of BIPN in patients with multiple myeloma. A total of 22 patients with multiple myeloma who developed peripheral neuropathy after receiving bortezomib-based chemotherapy will be e…
Phase: NA • Sponsor: The First Affiliated Hospital of Zhejiang Chinese Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Heat therapy could zap thyroid nodules without surgery
Disease control Recruiting nowThe purpose of this observational chart review study is to evaluate the efficacy and safety of Radiofrequency Ablation (RFA) for treatment of indeterminate thyroid nodules before and after RFA procedure. This is a data collection study in which the investigators ask patients to g…
Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Lung clues could unlock early rheumatoid arthritis detection
Knowledge-focused CompletedThe study is designed to learn more about the causes of rheumatoid arthritis (RA). People who get RA have elevated protein markers called autoantibodies in their blood years before initial symptoms of arthritis. The goal of this study is to learn more about how autoantibodies in …
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Mystery autumn allergies traced to birch rust?
Knowledge-focused CompletedIn this project we study if spores from birch rust fungi (Melampsoridium Betulinum = MB) may be the eliciting allergen in patients with seasonal airway allergy during autumn in North Norway. Patients with suspected allergy to MB are compared with non-allergic controls using data …
Sponsor: University Hospital of North Norway • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC