Opioid may tame dangerous blood pressure jumps during breathing tube insertion
NCT ID NCT07348159
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether nalbuphine, an opioid painkiller, can prevent sudden increases in blood pressure and heart rate when a breathing tube is placed during general anesthesia. 107 adults having elective surgery were randomly given either nalbuphine or a placebo before anesthesia. Researchers measured blood pressure and heart rate at several time points to see if nalbuphine kept these levels more stable.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nalbuphine
What this could lead to
If it works, this could give doctors a simple way to keep blood pressure stable during anesthesia, reducing risks for some patients.
What could go wrong
This is a small, completed trial with 107 people. The results may not apply to all patients, and nalbuphine is an opioid with side effects like nausea or drowsiness.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND OROTRACHEAL INTUBATION are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Hayatabad Medical Complex
Peshawar, Khyber Pakhtunkhwa, 25000, Pakistan