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127005 trials found · Page 3493 of 6351
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Can a modified camera capture better images of diseased retinas?
Knowledge-focused Recruiting nowImages will be collected on the modified P200TE
Sponsor: Optos, PLC • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Can inhaled sedation save money and improve outcomes for ventilated ICU patients?
Knowledge-focused Not yet recruitingThe goal of this observational study is to learn whether inhaled sedation is a cost-effective alternative to intravenous propofol in mechanically ventilated critically ill adults admitted to the intensive care unit. The main questions it aims to answer are: * Does inhaled sedati…
Sponsor: Hospital H+ Queretaro • Aim: Knowledge-focused
Last updated Jul 31, 2026 00:00 UTC
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Simple foot exercises may offer Drug-Free relief for chronic heel pain
Symptom relief Not yet recruitingThis study aims to compare the effects of foot core strengthening and sensorimotor re-training, each combined with routine physical therapy, on pain, functional ability, and plantar pressure in patients with Plantar Fasciitis. Participants will be divided into two groups: one re…
Sponsor: Lahore University of Biological and Applied Sciences • Aim: Symptom relief
Last updated Jul 16, 2026 00:00 UTC
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Can a once-daily pill help manage obesity? a new trial puts an experimental drug to the test.
Disease control Not yet recruitingThis study will look at a study drug called PF-08642534 in people with obesity (have too much body weight) to see: if participants can take different amounts (doses) of the study drug in a safe way and how adults with obesity tolerate it, and how the body handles the study drug (…
Phase 1 • Sponsor: Pfizer • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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Injection targets double chin fat without surgery
Symptom relief Recruiting nowThis Phase 2 study aims to assess the efficacy of SC injections of STP705 for the reduction of Submental fat in apopulation of healthy adult volunteers, and to further establish its safety and tolerability. The primary objective is to evaluate the efficacy of STP705 injection fo…
Phase 2 • Sponsor: Sirnaomics • Aim: Symptom relief
Last updated Aug 12, 2026 00:00 UTC
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Could nail biting reshape the jaw? X-Rays may reveal hidden effects
Knowledge-focused Not yet recruitingNail biting (onychophagia) is a common parafunctional habit characterized by repetitive and non-functional biting behavior. Although the effects of nail biting on dental structures and occlusion have been reported, its potential effects on mandibular bone structure remain unclear…
Sponsor: Recep Tayyip Erdogan University Training and Research Hospital • Aim: Knowledge-focused
Last updated Aug 05, 2026 00:00 UTC
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Can a warmer, wetter breath during surgery protect the lungs?
Knowledge-focused Recruiting nowGeneral anesthesia with endotracheal intubation bypasses the physiological warming and humidification functions of the upper airway, allowing cold and dry gases to reach the lower respiratory tract. This may impair mucociliary clearance, increase secretion viscosity, promote atel…
Sponsor: Marmara University • Aim: Knowledge-focused
Last updated Jul 29, 2026 00:00 UTC
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Could lying flat vs. on your side change esophageal test results?
Knowledge-focused Recruiting nowThis is a prospective, single-center, crossover study comparing EndoFLIP measurements obtained in two patient positions, supine and left lateral decubitus, in pediatric and young adult patients. The Endoluminal Functional Lumen Imaging Probe (EndoFLIP) is an FDA-approved device f…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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Can involving families in hospital care respect patient rights?
Knowledge-focused Recruiting nowThis qualitative study will explore how family-centred care is understood and experienced in adult inpatient medical wards in the UK. Family-centred care involves including a patient's family in care and discussions where appropriate. Although family involvement can improve commu…
Sponsor: Milton Keynes University Hospital NHS Foundation Trust • Aim: Knowledge-focused
Last updated Aug 02, 2026 00:00 UTC
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Can tracking heart-kidney-metabolic syndrome in india reveal its hidden patterns?
Knowledge-focused Not yet recruitingThe goal of this observational registry study is to learn about cardiovascular-kidney-metabolic syndrome, also called CKMS, among adults receiving care at tertiary care hospitals in India. CKMS describes the close relationship between excess body weight, metabolic conditions such…
Sponsor: Centre for Chronic Disease Control, India • Aim: Knowledge-focused
Last updated Jul 24, 2026 00:00 UTC
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Could a short course of physiotherapy improve posture and ease pain after breast reduction?
Symptom relief By invitation onlyBackground and Purpose: Breast reduction surgery is a major procedure that can lead to post-operative pain, postural deviations, and a temporary decline in quality of life.This clinical study aims to investigate the efficacy of early-phase physical therapy on pain management, po…
Sponsor: Istanbul Rumeli University • Aim: Symptom relief
Last updated Jul 29, 2026 00:00 UTC
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Can a new experimental pill be safely given to people?
Knowledge-focused Recruiting nowTo evaluate the tolerability and safety of a single oral dose of ZL-65 tablets in healthy adult trial participants through dose escalation; and to preliminarily assess the pharmacokinetic and pharmacodynamic characteristics of a single oral dose of ZL-65 tablets.Exploring the imp…
Phase 1 • Sponsor: Chengdu Zenitar Biomedical Technology Co., Ltd • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
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Experimental drug takes aim at deadly lung complication
Disease control Recruiting nowThis is a proof of concept study to determine if Emapalumab appears effective for the treatment of anti-MDA5 antibody positive rapidly progressive interstitial lung disease (MDA5 RP-ILD). Emapalumab is a medication that is currently used for a severe problem with the immune syste…
Phase 2 • Sponsor: University of Miami • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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Can we predict who will sleep poorly after lung surgery?
Knowledge-focused Not yet recruitingThis study combines retrospective data analysis with a single-center prospective non-interventional cohort study to understand postoperative sleep disturbance on the first night after video-assisted thoracoscopic (VATS) lobectomy or segmentectomy. It mainly wants to answer the qu…
Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC
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Could a VR headset replace painkillers for toenail surgery?
Symptom relief Recruiting nowIngrown toenail is a common condition that may cause significant pain, functional impairment, and recurrent disease. Although conservative management is appropriate for mild cases, moderate-to-severe or recurrent ingrown toenails are commonly treated surgically under local anesth…
Sponsor: Ankara City Hospital Bilkent • Aim: Symptom relief
Last updated Sep 03, 2026 00:00 UTC
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Breathing training may ease acid reflux without drugs
Symptom relief Not yet recruitingThe goal of this clinical trial is to learn if inspiratory muscle training (IMT) works to treat on clinical symptom severity and quality of life in patients with Non-erosive reflux disease (NERD). The main questions it aims to answer are: Does drug IMT lower the clinical symptom…
Sponsor: Izmir University of Economics • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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Will a new tablet match the capsule for hot flash relief?
Knowledge-focused Recruiting nowThis study is being done to compare two forms of the medicine elinzanetant, which is used to help manage hot flush symptoms related to changes in female hormones. The researchers want to find out whether a new tablet form of elinzanetant is absorbed and processed by the body of h…
Phase 1 • Sponsor: Bayer • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC
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What keeps earthquake survivors going? a study asks
Knowledge-focused OngoingThe aim of this study was to explore the perspectives of individuals who experienced the Kahramanmaraş earthquake through a qualitative approach.
Sponsor: Zülal TATAR • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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Can Kids' bodies handle the heat during exercise? a new study investigates
Knowledge-focused By invitation onlyLittle is known about how children and youth regulate body temperature during exercise in the heat compared with young adults, including whether differences in whole-body heat exchange contribute to their responses. The goal of this clinical trial is to determine how exercise int…
Sponsor: University of Ottawa • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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New cream targets itch in eczema patients
Symptom relief Recruiting nowThis study is being done to obtain descriptive classifications of pruritus using a patient directed survey system and assess change in pruritus over time in patients with Atopic Dermatitis over 4 weeks with use of topical Roflumilast cream 0.15% QD.
Phase 4 • Sponsor: Integrative Skin Science and Research • Aim: Symptom relief
Last updated Aug 15, 2026 00:00 UTC