New hope for aggressive brain tumors: experimental drug targets genetic weakness
NCT ID NCT05588141
First seen Oct 31, 2025 · Last updated May 20, 2026 · Updated 24 times
Summary
This study tests an experimental drug called zotiraciclib for people with a specific type of brain tumor (glioma) that has returned after treatment. The tumors must have a mutation in the IDH1 or IDH2 gene. The goal is to see if the drug can slow or stop tumor growth. Participants take the drug by mouth on a set schedule over 28-day cycles and are monitored with monthly clinic visits and MRI scans every 8 weeks.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-••••
Conditions
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