Can a lotus seed extract help menopausal women sleep through the night?

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female, aged 40-65 years at time of enrollment * Confirmed menopausal status: (a) natural menopause (≥12 consecutive months of amenorrhea without other clinical cause), or (b) surgical menopause (bilateral oophorectomy with documented date of procedure) * Positive onboarding sleep screener: rates sleep quality as "Fairly Bad" or "Very Bad" AND reports sleep difficulty at least once per week in the prior month * PSQI global score \>5 at T0 baseline assessment (formal eligibility gate) * Owns and actively uses an Oura Ring Generation 4 at time of enrollment * Demonstrates ≥80% Oura Ring wear compliance in the 30 days prior to enrollment, confirmed via Alethios platform sync at onboarding * Willing to wear Oura Ring Generation 4 continuously for 42 nights throughout the study period * Willing to maintain stable diet, sleep habits, medications, and supplement use throughout the 42-day study period * No planned major disruptions to sleep schedule, shift work, or travel across ≥3 time zones during the study period * Access to a smartphone or computer to complete eConsent and digital questionnaires * Able to provide informed consent via the Alethios eConsent platform Exclusion Criteria: * Current use of prescription sleep medications (benzodiazepines, non-benzodiazepine hypnotics, doxepin, suvorexant) within 30 days of enrollment * Current use of melatonin supplements at doses \>1 mg/day within 14 days of enrollment * Diagnosis of a clinically significant sleep disorder requiring treatment (obstructive sleep apnea unless adequately treated and stable, restless legs syndrome, narcolepsy) * Diagnosis of a major psychiatric disorder currently requiring pharmacological treatment * Current use of hormone replacement therapy initiated within 90 days of enrollment, or any planned changes to HRT during the study (stable long-term HRT is acceptable) * Regular use of GABAergic, serotonergic, or sedating supplements (valerian, passionflower, ashwagandha, kava) within 14 days of enrollment * Shift work or schedule regularly requiring sleep between 06:00 and 22:00 * Planned travel across 3 or more time zones during the 42-day study period * Known allergy to lotus, rice, or related botanicals * Active cardiovascular, hepatic, renal, or neurological condition that in the PI's judgment would affect sleep or participant safety * Participation in another interventional study within 30 days of enrollment * In the opinion of the PI, any condition compromising participant safety or data integrity