Can a new pill bring back skin color in vitiligo?
NCT ID NCT07108283
First seen Nov 10, 2025 · Last updated Jun 23, 2026 · Updated 30 times
Summary
This study tests a drug called zasocitinib in adults with nonsegmental vitiligo, an autoimmune condition that causes white patches on the skin. About 200 participants will take either the drug or a placebo for up to a year. The main goal is to see if the drug can improve skin color on the face by at least 75% after 6 months.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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ACRC Trials
RECRUITINGPlano, Texas, 75024, United States
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Advanced Clinical Research Institute (ACRI)
RECRUITINGTampa, Florida, 33607, United States
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Arke SMO SA de CV
NOT_YET_RECRUITINGVeracruz, 91900, Mexico
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Assistance Publique-Hopitaux de Paris (AP-HP) - Hopitaux Universitaires Henri Mondor (Hopital Henri-Mondor)
NOT_YET_RECRUITINGCréteil, 94010, France
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Azienda Usl Toscana Centro
NOT_YET_RECRUITINGFlorence, 50125, Italy
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Bexley Dermatology (legal entity - Dermatologists of Southwestern Ohio, LLC)
WITHDRAWNBexley, Ohio, 43209, United States
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Bordeaux University Hospital
NOT_YET_RECRUITINGBordeaux, 33000, France
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Brunswick Dermatology Center (BDC)
RECRUITINGFredericton, New Brunswick, E3B 1G9, Canada
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CRI Centro Regiomontano de Investigation SC
NOT_YET_RECRUITINGMonterrey, New Leon, 64060, Mexico
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Cabinet Medical du Dr Ruer
NOT_YET_RECRUITINGMartigues, 13500, France
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Center for Dermatology Clinical Research, Inc.
RECRUITINGFremont, California, 94538, United States
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Centre Hospitalier Le Mans (CHM)
NOT_YET_RECRUITINGLe Mans, 72000, France
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Centre Hospitalier Universitaire (CHU) de Toulouse - Hopital Larrey
NOT_YET_RECRUITINGToulouse, 31059, France
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Centre Hospitalier Universitaire de Nice - Hopital l'Archet
NOT_YET_RECRUITINGNice, 6202, France
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Centre de Recherche Dermatologique de Quebec
RECRUITINGQuébec, Quebec, G1V 4X7, Canada
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Centro de Dermatologia de Monterrey
NOT_YET_RECRUITINGMonterrey, Nuevo León, 64460, Mexico
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Clinica Universidad de Navarra
RECRUITINGMadrid, 28027, Spain
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Clinica de Enfermedades Cronicas y de Procedimientos Especiales
NOT_YET_RECRUITINGMorelia, Predeterminado, 58249, Mexico
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DelRicht Research (Audubon Dermatology)
RECRUITINGNew Orleans, Louisiana, 70115, United States
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DelRicht Research - Dermatology
RECRUITINGBaton Rouge, Louisiana, 70809, United States
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Dermatology Trial Associates
RECRUITINGBryant, Arkansas, 72022, United States
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Dermedic Jacek Zdybski
RECRUITINGKielce, Świętokrzyskie Voivodeship, 25-553, Poland
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Dermodent Centrum Medyczne Aldona Czajkowska Rafal Czajkowski
RECRUITINGOsielsko, Kuyavian-Pomeranian Voivodeship, 86-031, Poland
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Dermoklinika Centrum Medyczne
RECRUITINGLodz, Łódź Voivodeship, 90-436, Poland
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ETG Warszawa
RECRUITINGWarsaw, 02-677, Poland
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Encore Medical Research of Boynton Beach LLC.
RECRUITINGBoynton Beach, Florida, 33436, United States
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Encore Medical Research of Weston LLC
RECRUITINGWeston, Florida, 03331, United States
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First Affiliated Hospital of Xi 'an Jiaotong University
NOT_YET_RECRUITINGXi'an, Shaanxi, 100176, China
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First OC Dermatology
RECRUITINGFountain Valley, California, 92708, United States
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Fondazione Policlinico A. Gemelli
RECRUITINGRome, 00168, Italy
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Gyncentrum Sp. z o.o.
RECRUITINGKatowice, 40-600, Poland
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Hamzavi Dermatology - Canton
RECRUITINGCanton, Michigan, 48187, United States
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Hangzhou Third People's Hospital
RECRUITINGHangzhou, Zhejiang, 310009, China
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Hospital Universitario La Paz (HULP)
RECRUITINGMadrid, 28034, Spain
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Hospital Universitario Ramon y Cajal
RECRUITINGMadrid, 28034, Spain
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Hospital Universitario Reina Sofia
RECRUITINGCórdoba, 14004, Spain
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Hospital Universitario de Gran Canaria Doctor Negrin
RECRUITINGLas Palmas de Gran Canaria, Las Palmas, 35010, Spain
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Hospital de Manises
RECRUITINGValencia, 46005, Spain
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Huashan Hospital of Fudan University
RECRUITINGShanghai, Shanghai Municipality, 200040, China
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Humanitas Research Hospital
NOT_YET_RECRUITINGRozzano, Milan, 20089, Italy
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Istituto Dermopatico Immacolata IDI, IRCCS
RECRUITINGRome, Roma, 00167, Italy
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Klinika Dermatologii i Dermatologii Onkologicznej Uniw. Szp. Klin. in Rzeszow
RECRUITINGRzeszów, 35-055, Poland
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Kume Clinic - Sakai
RECRUITINGNishi-ku, Osaka, 593-8324, Japan
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LEADER research
RECRUITINGHamilton, Ontario, L8L 3C3, Canada
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Lawrence J Green LLC
RECRUITINGRockville, Maryland, 20850, United States
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Markowitz Medical dba Optiskin
RECRUITINGNew York, New York, 10128, United States
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Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
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Mount Sinai
WITHDRAWNNew York, New York, 10028, United States
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Nagoya City University Hospital
RECRUITINGNagoya, Aichi-ken, 467-8602, Japan
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Nippon Medical School Hospital
RECRUITINGBunkyo-ku, Tokyo, 113-8603, Japan
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North York Research Inc
RECRUITINGToronto, Ontario, M2N 3A6, Canada
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Progressive Clinical Research-San Antonio
RECRUITINGSan Antonio, Texas, 78213, United States
Contact
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SKiN Centre for Dermatology
RECRUITINGPeterborough, Ontario, K9J 5K2, Canada
Contact
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San Marcus Research Clinic, Inc.
RECRUITINGMiami Lakes, Florida, 33014, United States
Contact
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SimcoDerm Medical and Surgical Dermatology Centre
RECRUITINGBarrie, Ontario, L4M 7G1, Canada
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Skinsense Medical Research
RECRUITINGSaskatoon, Saskatchewan, S7K 2C1, Canada
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Spedali Civili Hospital
NOT_YET_RECRUITINGBrescia, 25123, Italy
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Texas Dermatology and Laser Specialists
RECRUITINGSan Antonio, Texas, 78218, United States
Contact
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The Centre for Clinical Trials
RECRUITINGOakville, Ontario, L6J 7W5, Canada
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The First Affiliated Hospital of Kunming Medical College
NOT_YET_RECRUITINGKunming, Yunnan, 650032, China
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The First Hospital of Wuhan
RECRUITINGWuhan, Hubei, 430022, China
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The Vitiligo & Pigmentation Institute of Southern California
RECRUITINGLos Angeles, California, 90036, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Therapeutics Clinical Research
RECRUITINGSan Diego, California, 92123, United States
Contact
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Toho University-Sakura Hospital Medical Center
RECRUITINGSakura-shi, Chiba, 285-8741, Japan
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Tokyo Medical University Hospital
RECRUITINGTokyo, TAkyA, 160-0023, Japan
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Twoja Przychodnia Szczecinskie Centrum Medyczne Sp. z o.o.
RECRUITINGSzczecin, West Pomeranian Voivodeship, 71-212, Poland
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UC Davis Department of Dermatology
RECRUITINGSacramento, California, 95816, United States
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UT Health Science Center Houston
RECRUITINGBellaire, Texas, 77401, United States
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Weill Cornell Medicine
RECRUITINGNew York, New York, 10075, United States
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dermMedica Sp. z o.o.
RECRUITINGWroclaw, Lower Silesian Voivodeship, 51-503, Poland
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
zasocitinib (also known as TAK-279)
What this could lead to
If it works, this could lead to a new treatment option that helps restore skin color in people with vitiligo.
What could go wrong
This is an early Phase 2 trial with only 200 participants, so results may not apply to everyone. The drug may not work better than placebo, and side effects are still being studied.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.