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Baby tooth wipes show promise in fighting cavity bugs

NCT ID NCT07245433

Prevention Sponsor: Alexandria University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether daily use of xylitol wipes can reduce cavity-causing bacteria in infants and toddlers. Twenty healthy children aged 9 to 18 months had their teeth and gums wiped three times a day for four weeks. Researchers measured bacteria and acid levels in saliva to see if the wipes helped.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
xylitol dental wipes
What this could lead to
If effective, xylitol wipes could offer a simple, daily way to help prevent early childhood cavities in babies and toddlers.
What could go wrong
This is a very small, early study with only 20 children and no comparison group. Results may not apply to all children, and long-term cavity prevention is not proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Jan 2024

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

9 to 18 months

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Healthy infants and toddlers aged 9 months to 18 months Caries-free (no visible dental decay or white spot lesions) Cooperative child and mother willing to participate for 4 weeks Mother able to understand and follow instructions for xylitol wipe use Written informed consent obtained from parent or legal guardian Exclusion Criteria: Infants or toddlers with systemic diseases or medical conditions affecting saliva Use of antibiotics or antimicrobial mouth products within the past 4 weeks Known allergy or sensitivity to xylitol or product components Existing oral lesions or ongoing dental treatment Non-compliance with study protocol or loss to follow-up

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Conditions

The condition(s) this trial relates to.

dental caries prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental caries prevention Early childhood caries (ECC) Oral bacterial colonization Pediatric oral health

Contacts and locations

Locations

  • Faculty of Dentistry, Alexandria University

    Alexandria, Egypt, 21521, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.