New drug XmAb541 enters first human tests for tough cancers
NCT ID NCT06276491
First seen Mar 17, 2026 · Last updated Apr 30, 2026 · Updated 5 times
Summary
This early-stage study tests a new drug called XmAb541 in people with advanced ovarian, endometrial, or germ cell tumors that have not responded to prior treatments. The main goals are to check if the drug is safe and to find the best dose. About 282 participants will take part, and the study is currently recruiting.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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City of Hope
NOT_YET_RECRUITINGDuarte, California, 91010, United States
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Icahn School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10029, United States
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Indian University Melvin and Bren Simon Comprehensive Cancer Center
RECRUITINGIndianapolis, Indiana, 46202, United States
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Karmanos Cancer Institute
RECRUITINGDetroit, Michigan, 48201, United States
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
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Montefiore Einstein Comprehensive Cancer Center
RECRUITINGThe Bronx, New York, 10461, United States
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OU Health Stephenson Cancer Center
RECRUITINGOklahoma City, Oklahoma, 73104, United States
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SCRI Oncology Partners
RECRUITINGNashville, Tennessee, 37203, United States
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Stanford
NOT_YET_RECRUITINGPalo Alto, California, 94304, United States
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The John Theruer Cancer Center at Hackensack University Medical Center
RECRUITINGHackensack, New Jersey, 07601, United States
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The Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
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UPMC Hillman Cancer Center
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
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University of California
RECRUITINGSan Francisco, California, 94158, United States
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University of Chicago Medical Center
RECRUITINGChicago, Illinois, 60637, United States
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University of Virginia
RECRUITINGCharlottesville, Virginia, 22903, United States
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Winship Cancer Institute, Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
Conditions
Explore the condition pages connected to this study.