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New drug combo aims to help head and neck cancer patients avoid harsh chemo side effects

NCT ID NCT06110195

First seen Apr 03, 2026 · Last updated May 23, 2026 · Updated 8 times

Summary

This study tested a new drug called xevinapant combined with standard chemotherapy (carboplatin and paclitaxel) and radiation for people with advanced head and neck cancer who cannot take the usual chemo drug cisplatin. The main goal was to find the safest dose of xevinapant to use in future studies. The trial was stopped early, but the results help researchers understand how to better treat this group of patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Chicago Medicine Comprehensive Cancer Center

    Chicago, Illinois, 60637, United States

Conditions

Explore the condition pages connected to this study.