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Immune cells from donors target deadly blood cancers in early trial

NCT ID NCT04984356

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 23 times

Summary

This early-phase study tested a new treatment called WU-CART-007 in 28 people with T-cell acute lymphoblastic leukemia or lymphoblastic lymphoma that had come back or not responded to standard therapy. The treatment uses donor immune cells engineered to find and attack cancer cells. The main goals were to check safety and find the best dose. This is not a cure, but aims to control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027, United States

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • City of Hope

    Duarte, California, 91010, United States

  • Erasmus MC

    Rotterdam, Netherlands

  • Hospital Saint- Louis

    Paris, France

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Peter MacCallum Cancer Centre

    Melbourne, Victoria, Australia

  • Prinses Maxima Centrum

    Utrecht, Netherlands

  • University Hospital Robert Debre

    Paris, France

  • University of Wisconsin

    Madison, Wisconsin, 53792, United States

  • Vanderbilt University

    Nashville, Tennessee, 37212, United States

  • Washington University

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.