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Muscle loss in intestinal failure: could a simple protein and workout combo turn the tide?

NCT ID NCT07759271

Disease control Sponsor: Wang Xinying Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial tests whether adding whey protein supplements, resistance training, or both can improve muscle mass in adults with chronic intestinal failure and low muscle mass. Participants receive standard nutritional support and are randomly assigned to one of four groups: usual care, whey protein alone, resistance training alone, or the combination. Over six weeks, researchers track changes in muscle mass, strength, walking speed, and quality of life to see if these simple interventions can help.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
whey protein supplementation and resistance training
What this could lead to
If effective, this combination could offer a practical, non-drug way to preserve or build muscle in people with intestinal failure, improving strength and quality of life.
What could go wrong
The trial is small and short-term, so benefits may be modest or not lasting. Some participants may find the training or protein supplement difficult to tolerate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 72 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients with chronic intestinal failure and low muscle mass. 2. Willing to participate in the study and provide written informed consent. 3. Able to complete the assigned 6-week intervention and the assessments at baseline, week 6, and week 8. Exclusion Criteria: 1. Known allergy to whey protein. 2. Severe renal dysfunction.

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Conditions

The condition(s) this trial relates to.

chronic intestinal failure Intestinal Failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Intestinal failure Low muscle mass

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.