New study tests drug combo to fight Post-Surgery weight regain

NCT ID NCT05975580

Recruiting now Disease control Sponsor: University of California, Irvine Source: ClinicalTrials.gov ↗

First seen Feb 24, 2026 · Last updated May 20, 2026 · Updated 13 times

Summary

This study tests whether adding weight-loss medications (topiramate, phentermine, or both) to lifestyle counseling can help people who have regained weight after bariatric surgery. About 120 adults who had sleeve gastrectomy or gastric bypass at least 18 months ago and regained at least 5% of their lost weight will participate. The goal is to see if these drugs can safely and effectively reverse that regain.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Contact

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Locations

University of California Irvine Medical Center
RECRUITING

Orange, California, 92868, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Email: •••••@•••••

Conditions

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OBESITY