New study tests two simple tricks to shed pounds without pills or surgery
NCT ID NCT05143931
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two ways to help people with overweight or obesity lose weight: avoiding tempting situations (AVOID) or practicing self-control when faced with cravings (RESIST). About 500 adults will be followed for 12 months to see which approach works better for weight loss and healthier eating. The goal is to find practical strategies that people can use in daily life.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 503 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2022
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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14 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria (Main participants): * Age 18 years or older * BMI between 25-45 kg/m2 * Read, write, and speak English with acceptable visual acuity * Has a household member (≥ 14 years) willing to complete three brief assessments over 12 months\* \*Only applies to individuals who indicate they are cohabitating with at least one eligible household member Inclusion Criteria (Household participants): * 14-years-old * Parent consent for children \<18-years-old * Willingness to complete assessments / measurements Exclusion Criteria (Main participants): * Currently enrolled in weight loss interventions or undergoing bariatric surgery * Pregnant women * Individuals for whom weight loss may be contraindicated (e.g., unstable coronary artery disease, end-stage disease, active cancer treatment, uncontrolled insulin-dependent diabetes, portal hypertension, drug/alcohol abuse) * Individuals with severe cognitive delays or visual/hearing impairment * Individuals who are unable or unwilling to complete the study assessments / measurements Exclusion Criteria (Household participants): * ≤ 14-years-old * Individuals who are unable or unwilling to complete the study assessments / measurements
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Cedars-Sinai Medical Center
RECRUITINGLos Angeles, California, 90069, United States
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