Phone app aims to help young cancer survivors shed extra pounds
NCT ID NCT06848491
First seen Jun 27, 2026 · Last updated Aug 25, 2026 · Updated 2 times
Summary
This study tests a mobile health program designed to help young adults (ages 18-39) who have survived cancer and are now overweight or obese. Participants will either get a full weight management program through their phone or receive basic digital tools and support. The goal is to see if the tailored program helps them lose more weight over 6 months.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 240 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2025
- Expected to finish
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Oct 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 39 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18-39 years old at the time of consent. * Diagnosed with first invasive cancer between ages 15-39 years (self-report). * Within 10 years of diagnosis with no evidence of progressive disease or second primary cancers (self-report). * Completed active cancer directed therapy (cytotoxic chemotherapy, radiation therapy and/or definitive surgical intervention) at least six months prior to enrollment; may be receiving "maintenance" therapy to prevent recurrences (self-report). * Body mass index (BMI) of 25-50 kg/m2 Exclusion Criteria: * Type 1 diabetes or currently receiving certain medical treatments for Type 2 diabetes * Report a history of heart attack or stroke within previous 6 months * Health problems which preclude ability to walk for physical activity (e.g., lower limb amputation). Participants endorsing items 1-4 on the Physical Activity Readiness Questionnaire (PAR-Q) (experience of heart problems, frequent chest pains, or faintness or dizziness) will be excluded from the study. * Lost 5% or more of body weight (and kept it off) in the last 3 months * Lifetime history of clinical diagnosis or treatment of eating disorder (anorexia nervosa or bulimia nervosa), OR report of compensatory behaviors within the previous 3 months. If participant reports a history of compensatory behaviors, the investigators will review their information to determine eligibility. * Currently pregnant, pregnant within the past 6 months, or planning to become pregnant within the next 12 months * Untreated thyroid disease or any changes (type or dose) in thyroid medication in last 6 months * Hospitalization for depression or other psychiatric disorder within the past 12 months. * History of psychotic disorder or uncontrolled bipolar disorder * Currently participating in a weight loss, nutrition, or physical activity study or program or other study that would interfere with this study * Currently using prescription medications with known effects on appetite or weight (e.g., oral steroids, weight loss medications), with the exception of individuals on a stable dose of SSRIs for 3 months) * Previous surgical procedure for weight loss or planned weight loss surgery in the next year * Plans for major surgery (e.g., breast reconstruction) in the next 12 months * Inability to speak and read English * Does not reside in the United States * Do not have mobile phone with data plan or willing to be contacted by study through text messaging * No Internet access * Not willing to be randomized to either intervention arm
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of North Carolina at Chapel Hill
RECRUITINGChapel Hill, North Carolina, 27514, United States
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