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New combo therapy aims to boost weight loss and smoking cessation before bariatric surgery

NCT ID NCT07398404

First seen Feb 13, 2026 · Last updated Jun 16, 2026 · Updated 16 times

Summary

This study tests a program that combines medication (Naltrexone + Bupropion) with behavior therapy to help adults lose weight and quit smoking before bariatric surgery. Researchers will compare this approach to standard care in 64 participants aged 18-65 who smoke and have obesity. The goal is to see if the program is feasible and acceptable, and to measure weight change and smoking cessation.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Yale University

    New Haven, Connecticut, 06511, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Smoking Cessation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.