Weekly shot aims to shed pounds and soothe aching knees
NCT ID NCT07509307
First seen Apr 07, 2026 · Last updated May 01, 2026 · Updated 2 times
Summary
This study tests a new once-weekly injection (NNC0487-0111) in 400 adults with overweight or obesity and knee osteoarthritis. Participants are randomly assigned to receive either the study drug or a placebo. The goal is to see if the drug helps with weight loss and reduces knee pain and stiffness.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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"Zdrowie Osteo-Medic" s.c. Lidia i Artur Racewicz, Agnieszka i Jerzy Supronik
Bialystok, Podlaskie Voivodeship, 15-351, Poland
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ALPHA Recherche Clinique
Lévis, Quebec, G6V 0C9, Canada
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ALPHA Recherche Clinique
Québec, Quebec, G3K 2P8, Canada
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Aarhus Universitetshospital - Klinik for Led og bindevævssygdomme
Aarhus N, 8200, Denmark
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Adana Şehir Eğitim ve Araştırma Hastanesi-Fizik Tedavi ve Rehabilitasyon
Yuregir/Adana, 01060, Turkey (Türkiye)
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Advanced Res for Health Improve
Naples, Florida, 34102, United States
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Ankara Bilkent Şehir Hastanesi- Fizik Tedavi ve Rehabilitasyon
Çankaya/Ankara, 06800, Turkey (Türkiye)
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Arcturus Healthcare, PLC.
Troy, Michigan, 48098-6368, United States
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Athens Medical Center S.A. (Iatriko Athinon) - Diabetes and Obesity Unit
Marousi, 15125, Greece
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Athens Medical Center S.A. (Iatriko Psychicou) - Department of Internal Medicine & Metabolic Diseases
Athens, 11525, Greece
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Auxologico San Luca - Endocrinologia e Malattie del Metabolismo
Milan, Lombardy, 20149, Italy
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Azienda Ospedaliera Universitaria Integrata Verona - Ospedale Civile Maggiore Borgo Trento - U.O. Reumatologia
Verona, Veneto, 37126, Italy
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Bursa Yüksek İhtisas Eğitim ve Araştırma Hastanesi-Fizik Tedavi ve Rehabilitasyon
Yıldırım/Bursa, 16310, Turkey (Türkiye)
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CNS Healthcare
Jacksonville, Florida, 32256, United States
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Casa della Salute di Ceccano - Ambulatori Campus Biomedico
Rome, Lazio, 00128, Italy
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CenterMed Kraków Sp. z o.o.
Krakow, 31-530, Poland
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Centre Medical Acadie
Montreal, Quebec, H4N 2W2, Canada
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Centre de Recherche du CHUS
Sherbrooke, Quebec, J1H 5N4, Canada
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Centro Especialidades Hermanos Sangro
Madrid, 28038, Spain
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Centrum Medyczne Intercor Sp. z o.o.
Bydgoszcz, 85-605, Poland
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Chase Medical Research LLC
Waterbury, Connecticut, 06708, United States
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ClinicMed Daniluk, Nowak Spółka Komandytowa
Bialystok, 15-879, Poland
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Clinical Investigation Spec Gurnee
Gurnee, Illinois, 60031, United States
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Clinvest Research
Springfield, Missouri, 65807, United States
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Clínica Nuevas Tecnologías en Diabetes y Endocrinología
Seville, 41003, Spain
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Coastal Digestive Health
Maroochydore, Queensland, 4558, Australia
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Desert Oasis Healthcare
Palm Springs, California, 92262, United States
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Emeritus Research Sydney
Botany, New South Wales, 2019, Australia
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Evangelismos S.A. - Endocrinology department
Athens, 10676, Greece
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Evanston Premier Hlthcr Res
Skokie, Illinois, 60077, United States
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First Valley Medical Group
Lancaster, California, 93534, United States
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Frederiksberg Hospital - Parker Institutet (Artrose)
Frederiksberg, 2000, Denmark
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H. Infanta Luisa_Endocrino y Obesidad
Seville, 41010, Spain
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Health Res of Hampton Roads
Newport News, Virginia, 23606, United States
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Heart of Australia
Chelmer, Queensland, 4068, Australia
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Hospital For Special Surgery
New York, New York, 10021, United States
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Hospital General de Valencia
Valencia, 46014, Spain
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Hospital Germans Trias i Pujol
Badalona, 08916, Spain
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Hospital HM La Esperanza
Santiago de Compostela, 15705, Spain
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Hospital Infanta Sofía
San Sebastián de Los Reyes (Madrid), 28702, Spain
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Hospital Naval Ferrol
Ferrol, 15405, Spain
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Hospital Quirónsalud Málaga
Málaga, 29004, Spain
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Hospital Universitario Marqués de Valdecilla
Santander, 39008, Spain
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Instituto Medico Quirurgico San Rafael
A Coruña, 15006, Spain
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Istanbul Üniversitesi- Istanbul Tıp Fakültesi Esnaf Hastanesi Poliklinikleri Fiziksel Tıp Ve Rehabilitasyon Anabilim Dalı
Fatih/İstanbul, 34116, Turkey (Türkiye)
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Kolling Institute
St Leonards, New South Wales, 2065, Australia
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Laiko General Hospital Of Athens - 1st department of Internal Medicine
Athens, 115 27, Greece
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Latin Clinical Trial Center Puerto Rico
San Juan, 00909, Puerto Rico
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MC Dr. Atanasov EOOD
Sofia, 1231, Bulgaria
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MC Excelsior OOD
Sofia, 1407, Bulgaria
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MMA MHAT - Sofia, Rheumatology clinic
Sofia, 1606, Bulgaria
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Mercy Family Clinic
Dallas, Texas, 75208, United States
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Momentum Clinical Research Darlinghurst
Darlinghurst, New South Wales, 2010, Australia
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Monroe Biomedical Research, LLC
Louisville, Kentucky, 40213, United States
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NYU Langone Health
New York, New York, 10016, United States
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Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji im. prof. dr hab. med. Eleonory Reicher
Warsaw, 02-637, Poland
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Neighborhood Healthcare
Escondido, California, 92025, United States
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NextHealth S.A. - Department of Endocrinology, Metabolism & Diabetes
Thessaloniki, 54635, Greece
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Northwest Clinical Research Center
Bellevue, Washington, 98007, United States
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Northwest Research Center
Portland, Oregon, 97202, United States
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Ospedale Galeazzi S.p.A. - INCO - Istituto Nazionale per la Cura dell'Obesità
Milan, Lombardy, 20157, Italy
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Ospedale S. Maria della Misericordia - Reparto Endocrinologia e Malattie del Metabolismo
Udine, Friuli Venezia Giulia, 33100, Italy
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Piedmont Healthcare/Research
Statesville, North Carolina, 28625, United States
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Pol. Uni. Campus Biomedico - UOC Endocrinologia e Diabetologia
Rome, Lazio, 00128, Italy
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Policlinico San Donato di Milano S.p.A - UOS Endocrinologia e del Servizio di Nutrizione Clinica e Prevenzione Cardiometabolica
San Donato Milanese, Lombardy, 20097, Italy
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SBÜ Ankara Gaziler Fizik Tedavi Ve Rehabilitasyon Eğitim Ve Araştırma Hastanesi
Çankaya/Ankara, 06800, Turkey (Türkiye)
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Sanos Clinic - Herlev
Herlev, 2730, Denmark
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Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie Sp. z o.o.
Krakow, 31-826, Poland
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TLC Diabetes and Endocrinology
Surrey, British Columbia, V3T 2V6, Canada
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Thermi Clinic S.A. - Diabetes and Internal Medicine Department
Thessaloniki, 57001, Greece
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Trakya Üniversitesi Tıp Fakültesi Hastanesi-Fizik Tedavi ve Rehabilitasyon
Edirne, 22030, Turkey (Türkiye)
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UMHAT Sveti Georgi EAD, Plovdiv
Plovdiv, 4002, Bulgaria
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UMHAT Sveti Ivan Rilski EAD, Rheumatology
Sofia, 1612, Bulgaria
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UMHAT Tsaritsa Yoanna - ISUL EAD, Orthopaedics and Traumatology
Sofia, 1527, Bulgaria
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University General Hospital Attikon General Hospital Of West Attica H Agia Varvara - 2nd dept of Internal medicine
Chaïdári, Attica, 12461, Greece
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Westside Center For Clinical Research
Jacksonville, Florida, 32205, United States
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Your Research Network
Niagara Falls, Ontario, L2H 1H5, Canada
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İstanbul Fizik Tedavi ve Rehabilitasyon Eğitim ve Araştırma Hastanesi
Bahçelievler/İstanbul, 34186, Turkey (Türkiye)
Conditions
Explore the condition pages connected to this study.