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Warm anesthetics may cool down epidural fevers in childbirth

NCT ID NCT06682416

Symptom relief Sponsor: The First Affiliated Hospital of Soochow University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether warming the local anesthetic used in epidural pain relief to body temperature (37°C) can lower the chance of fever during labor. About 424 women from two hospitals will take part. Half will get the warmed solution, half will get room-temperature solution. Researchers will track fever rates, pain scores, and health outcomes for mothers and newborns.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
local anesthetic solution (warmed to 37°C)
What this could lead to
If it works, this could point toward a simple way to lower fever risk during epidural pain relief in childbirth.
What could go wrong
This is a small, early-stage study. The effect may be small or not apply to all women. Fever during labor has many causes, so warming the anesthetic may not help.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 424 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2024

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Requesting epidural analgesia; 2. Aged 18 or older; 3. At least 37 weeks of gestation; 4. Those delivering vaginally. Exclusion Criteria: 1. Contraindications to epidural analgesia; 2. Pre-existing fever (≥38°C) before labor; 3. Use of NSAIDs or other types of antipyretics before labor; 4. Multiple pregnancy (carrying more than one fetus); 5. Fetal demise (stillbirth); 6. Severe preeclampsia; 7. Women who refuse to participate.

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Conditions

The condition(s) this trial relates to.

agnosia Fever pain agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Analgesia, epidural Epidural related maternal fever Fever Intrapartum fever

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ethical Committee of the First Affiliated Hospital of Soochow University

    RECRUITING

    Suzhou, Jiangsu, 215000, China

  • Suzhou Municipal Hospital

    NOT_YET_RECRUITING

    Suzhou, Jiangsu, China

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