Walnut daily may clear Long-COVID brain fog, new study hints
NCT ID NCT07429903
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether eating 2 ounces of walnuts every day for 12 weeks could improve memory and reduce brain fog in adults over 40 with Long-COVID. About 31 people took part, comparing walnut eaters to those getting usual care. The goal was to see if walnuts, which are rich in healthy fats and plant chemicals, can ease common Long-COVID symptoms like memory trouble and fatigue.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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31 people
The number who actually took part.
- Started
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Sep 2023
- Finished
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Jan 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Age 40 years and older History of confirmed SARS-CoV-2 infection Presence of long-COVID symptoms lasting longer than 12 weeks, including one or more of the following: * Cognitive complaints ("brain fog," memory, attention, or processing speed difficulties) * Fatigue * Mood symptoms (e.g., depression) Consumption of a low-polyphenol (Western) diet Adequate visual acuity and hearing to complete neuropsychological testing Screening laboratory results without clinically significant abnormalities that would interfere with study participation Ability and willingness to provide written informed consent Exclusion Criteria: Diagnosis of probable Alzheimer's disease or other dementia (e.g., vascular, Lewy body, frontotemporal) Other neurological or medical conditions that may cause cognitive impairment Evidence of Parkinson's disease based on motor examination Uncontrolled hypertension (systolic BP \>170 mmHg or diastolic BP \>100 mmHg) Allergy to walnuts Regular consumption of more than 5 oz of walnuts per week Current diagnosis of a major psychiatric disorder according to DSM-5 criteria Alcoholism or substance use disorder Any condition that, in the investigator's judgment, would make participation unsafe or interfere with study completion
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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UCLA Center for Human Nutrition
Los Angeles, California, 90025, United States
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