Simple ladder and tap tests could spot early MS mobility changes
NCT ID NCT07505355
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at two new tests—a walking adaptability ladder test and a foot tap test—to see if they can detect subtle walking and movement problems in people with mild multiple sclerosis (MS). Researchers will compare results from 100 participants (people with mild MS and healthy volunteers) to see if these tests are reliable and valid. The goal is to find better ways to catch early mobility changes that standard tests might miss.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Participants will be recruited from the University of Leon, Ponferrada and Hospital Universitario de Ponferrada El Bierzo. A total of 50 persons with MS will be recruited and divided into two subgroups based on their disability level: EDSS 0-1.5 (n=25), EDSS 2.0-3.5 (n=25). 50 healthy controls, matched for age (considering a 5-year range per subject) and sex, will be recruited for comparison.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * confirmed diagnosis of definite MS, * relapse free at least 30 days, * Expanded Disability Status Scale (EDSS) score between 0 and 3.5 Exclusion Criteria: * diagnosed with neurological disease other than MS * cognitive decline that renders the patient incapable of performing tests and questionnaires. * other neurological, orthopedic, or visual impairments affecting gait
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
4 sites in 3 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hospital Universitario de Ponferrada El Bierzo
RECRUITINGLeón, Ponferrada, Spain
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Laboratorio di Biomeccanica ed Ergonomia industriale Università degli Studi di Cagliari
RECRUITINGCagliari, Italy
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REVAL Rehabilitation Research Center
RECRUITINGDiepenbeek, Belgium
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University of Leon
RECRUITINGLeón, Ponferrada, Spain
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Other studies related to the condition(s) this trial covers.
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