New combo therapy shows promise in taming chronic hepatitis b
NCT ID NCT05343481
First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 28 times
Summary
This study tested a new treatment called VTP-300 combined with a low dose of nivolumab in 121 adults with chronic hepatitis B who were already on antiviral medication. The goal was to see if the combination could lower hepatitis B surface antigen levels more than antivirals alone. The study was completed and focused on safety and how well the treatment worked.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Bamrasnaradura Infectious Diseases Institute
Nonthaburi, Thailand, 11000, Thailand
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Chang Gung Memorial Hospital Kaohsiung
Kaohsiung City, Taiwan
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Chia-Yi Christian Hospital
Chiayi City, Taiwan, 60002, Taiwan
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China Medical University Hospital
Taichung, Taiwan, 404332, Taiwan
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Chulabhorn Hospital
Bangkok, Thailand, 10210, Thailand
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Dalin Tzu Chi Hospital
Chiayi City, Taiwan
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HIV Netherlands-Australia-Thailand Research Collaboration
Bangkok, Thailand, Thailand
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Hospital For Tropical Diseases
Bangkok, Thailand
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Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung, Taiwan, 807, Taiwan
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King Chulalongkorn Memorial Hospital
Bangkok, Thailand, 10330, Thailand
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Linkou Chang Gung Memorial Hospital
Taoyuan City, Taiwan, 333, Taiwan
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Maharaj Nakorn Chiang Mai Hospital
Chiang Mai, Thailand, 50200, Thailand
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National Cheng Kung University Hospital
Tainan, Taiwan, 704, Taiwan
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National Taiwan University Hospital
Taipei, Taiwan
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Prince Of Wales Hospital
Hong Kong, Hong Kong
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Queen Mary Hospital
Hong Kong, Hong Kong
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Research Institute For Health Sciences
Chiang Mai, Thailand
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Srinagarind Hospital
Khon Kaen, Thailand
Conditions
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