Heart mapping study seeks clues to dangerous rhythms in genetic AF patients
NCT ID NCT06647459
First seen Feb 19, 2026 · Last updated Jun 22, 2026 · Updated 16 times
Summary
This study aimed to understand why some people with genetic early-onset atrial fibrillation (AF) are at risk for a dangerous heart rhythm called ventricular tachycardia (VT). Researchers used special heart mapping during a standard AF ablation procedure in 32 adults. The goal was to compare heart tissue and electrical patterns between those with a specific genetic variant (TTN) and those without, to better predict VT risk.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors better predict dangerous heart rhythms in people with certain genetic forms of atrial fibrillation.
What could go wrong
This trial was terminated early with only 32 participants, so results may be limited. It is an observational mapping study, not a treatment test.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.