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VR games could replace traditional physio for knee pain

NCT ID NCT06639867

Symptom relief Sponsor: Cardiff University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a home-based virtual reality system can help people with knee osteoarthritis do their physiotherapy exercises in a more engaging way. Fifty adults aged 45 and older with knee pain will be randomly assigned to either the VR program or standard physiotherapy. The main goal is to see if a larger trial is possible, not yet to prove the treatment works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
non-immersive virtual reality physiotherapy system
What this could lead to
If it works, this could offer a more engaging and convenient way to do physiotherapy at home for knee osteoarthritis pain.
What could go wrong
This is a very small feasibility study with only 50 people, so results may not apply widely. The VR system may cause motion sickness or falls, and it is not yet proven to be better than standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2024

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 45 or older years * Clinical diagnosis of knee osteoarthritis * Referred for physiotherapy for clinically diagnosed knee osteoarthritis pain * Activity related joint pain * Self-reported knee pain on most days for the past 3 months * Average pain severity in the past week of 4 or greater on a 10-point numeric rating scale * Able to understand written and spoken English * Able to provide written informed consent Exclusion Criteria: * Where knee is not identified by the participant as the main source of pain (e.g. comorbid painful conditions, widespread pain). * Contraindication to exercise * Pain caused by malignancy, fractures, or inflammatory arthritis * Has received surgery for their knee pain in the last 12 months * Has commenced another new treatment for knee pain, including intra-articular injection, during the preceding 12 weeks * Concurrent ongoing treatment by physiotherapy other than the trial interventions * Previous knee arthroplasty in either knee * Unable to walk without a walking aid * Unable or unwilling to engage in either active or control intervention

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee osteoarthritis

Contacts and locations

Locations

  • Cardiff University School of Healthcare Sciences

    Cardiff, United Kingdom

  • University Hospital of Wales

    Cardiff, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.