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Which treatment saves your voice better? surgery vs. radiation for early throat cancer

NCT ID NCT04447456

Knowledge-focused Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 41 people who had early-stage vocal cord cancer and were treated with either surgery or radiation. The goal was to see which treatment led to better voice quality five years later. Patients filled out a questionnaire about their voice, and doctors also measured voice features. The results may help guide future treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If one treatment clearly leads to better voice quality, it could help doctors and patients choose the best option for early vocal cord cancer.
What could go wrong
This is a small, completed observational study with only 41 participants. It does not test a new treatment, so it cannot prove which therapy is better overall.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

41 people

The number who actually took part.

Started

Nov 2020

Finished

Jan 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

patients treated for glottic squamous cell carcinoma at Lille University Hospital and the Oscar Lambret Centre between 2015 and 2017.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with glottic squamous cell carcinoma T1N0M0 who may benefit from treatment with exclusive radiotherapy or exclusive surgery. * patients treated for these cancers at Lille University Hospital and the Oscar Lambret Centre between 2015 and 2017. * Tis, T1a and T1b glottic squamous cell carcinomas according to the TNM 7th edition classification in long-term survivors. Exclusion Criteria: \-

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Conditions

The condition(s) this trial relates to.

glottis carcinoma glottis squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Glottic carcinoma

Contacts and locations

Locations

  • Centre Oscar Lambret

    Lille, 59000, France

  • Hôpital Huriez, CHU

    Lille, France

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