Could vitamin d levels predict PCOS risks in teens?
NCT ID NCT06970821
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This completed study looked at 70 adolescent girls with PCOS and 40 healthy teens to see if vitamin D levels are linked to metabolic problems like insulin resistance. Researchers measured vitamin D, blood sugar, cholesterol, and belly fat thickness using ultrasound. The goal was to better understand early heart and metabolic risks in teens with PCOS.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If clear links are found, this could point toward vitamin D screening or supplementation as a way to manage metabolic risks in teens with PCOS.
- What could go wrong
- This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
106 people
The number who actually took part.
- Started
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Mar 2024
- Finished
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May 2025
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Female adolescents aged 13 to 19 years who attended the adolescent gynecology outpatient clinic of a tertiary care hospital. Participants included adolescents diagnosed with polycystic ovary syndrome based on NIH criteria and age-matched healthy controls. All participants had attained menarche at least two years prior to enrollment.
- Ages
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13 to 19 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female adolescents aged 13 to 19 years * Having attained menarche at least two years prior to enrollment * For PCOS group: Diagnosis of polycystic ovary syndrome based on NIH criteria (presence of menstrual irregularity and clinical and/or biochemical hyperandrogenism) * For Control group: Regular menstrual cycles (cycle interval 21-35 days) and no clinical or biochemical signs of hyperandrogenism. Exclusion Criteria: * Use of medications affecting vitamin D metabolism, insulin sensitivity, or androgen levels within the past 6 months (e.g., oral contraceptives, insulin sensitizers, vitamin D supplements) * Presence of endocrine disorders such as congenital adrenal hyperplasia, hyperprolactinemia, Cushing's syndrome, thyroid dysfunction. * Chronic systemic diseases (e.g., diabetes mellitus, severe liver or kidney disease).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Bağcılar Training and Research Hospital
Istanbul, 34200, Turkey (Türkiye)
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