Vitamin d Mega-Doses tested for epilepsy relief
NCT ID NCT06736002
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether high doses of vitamin D, followed by a lower maintenance dose, can reduce seizure frequency, fatigue, and improve quality of life in adults with epilepsy. Two hundred participants will receive vitamin D supplements and be monitored for three months. The goal is to see if this simple vitamin can offer extra help alongside standard epilepsy treatments.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Vitamin D
- What this could lead to
- If it works, this could point toward a simple, low-cost vitamin supplement to help manage seizures and fatigue in people with epilepsy.
- What could go wrong
- This is an early-stage study with no control group comparison yet. Vitamin D is not a standard epilepsy treatment, and results may not show clear benefits or may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 20 or above (inclusive) * Diagnosed patients (refractory epilepsy refers to those who have used more than two drugs, and each drug has reached the When epileptic seizures cannot be well controlled at standard reasonable treatment doses, it is called refractory epilepsy) * There is no imaging evidence of persistence or expansion of brain damage in the past three years * Subjects or family members (caregivers) can comply with the trial plan and take vitamin D patients Exclusion Criteria: \-
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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National Cheng Kung University Hospital
RECRUITINGTainan, 704, Taiwan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can video games rewire young brains after injury?
- High-Fat Diet's effect on epilepsy: scientists track brain signals
- Epilepsy drug candidate put to the test in healthy volunteers