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Vitamin D's secret role in blood pressure revealed?

NCT ID NCT03348280

Knowledge-focused Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how vitamin D levels might influence high blood pressure in people with type 2 diabetes. Researchers will collect blood samples from 40 participants to study immune cells called monocytes and see if they trigger a hormone that raises blood pressure. The goal is to better understand the connection, not to test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2017

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

T2DM patients with hypertension

Ages

25 to 80 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Type 2 diabetes (T2DM) * Age: 25-80 years old * Vitamin 25(OH)D3 levels \<20 or \>30 ng/ml. * HbA1c: 5.5%-9.5% * Blood Pressure: \<160/100 mm Hg on BP lowering medications and * Blood Pressure: \>120/80 to 160/100 mmHg without BP lowering medications Exclusion Criteria: * Recent weight loss of more than 5% within 3 months prior to screening * Current Pregnancy * Hypercalcemia * Previous heart attack and stroke * Heart failure * Atrial fibrillation * Heavy alcohol consumption * Extreme diets (Atkins, South Beach) * Chronic renal failure: stage 4 or worse * \>2 + proteinuria on urine sample * Chronic diseases known to affect immunity

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Conditions

The condition(s) this trial relates to.

hypertensive disorder type 2 diabetes mellitus vitamin D deficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diabetes mellitus type 2 Hypertension Vitamin D deficiency

Contacts and locations

Locations

  • Barnes-Jewish & Washington University Diabetes Center

    St Louis, Missouri, 63110, United States

  • Washington University

    St Louis, Missouri, 63110, United States

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Other studies related to the condition(s) this trial covers.