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Vitamin d deficiency common in heart failure patients – does supplementation help?

NCT ID NCT01993537

Knowledge-focused Sponsor: Ottawa Heart Institute Research Corporation Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how common vitamin D deficiency is in people with chronic heart failure and whether giving vitamin D supplements improves their health. 91 adults with heart failure were divided into groups based on their vitamin D levels. Those with severe deficiency were randomly chosen to receive vitamin D or no treatment. Researchers tracked hospital visits, deaths, and lab results over 26 months to see if supplements made a difference.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

91 people

The number who actually took part.

Start date

Jan 2013

Finished

Jan 2016

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * an ejection fraction (EF) ≤40% within the last 12 months before recruitment * established diagnosis of heart failure * \>18 years of age * patients with Vitamin D levels of sufficient, mild deficiency and severe deficiency Exclusion Criteria: * hypercalcemia * known hypersensitivity to Vitamin D * patient unwilling to comply with study requirements * any other disease other than heart failure that can alter the patients quality of life over a period of 6 months * women of child bearing potential * a patient currently taking vitamin d * severe renal impairment eGFR \<30

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Conditions

The condition(s) this trial relates to.

congestive heart failure vitamin D deficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic heart failure Vitamin D deficiency

Contacts and locations

Locations

  • The University of Ottawa Heart Institute

    Ottawa, Ontario, K1Y 4W7, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.