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Virtual walking could ease nerve pain in spinal cord injury patients

NCT ID NCT05005026

Symptom relief Sponsor: Texas A&M University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether playing a virtual reality walking game at home can help reduce neuropathic pain in adults with chronic spinal cord injury. 250 participants with complete injuries will use a VR headset to see virtual legs walking from a first-person view. They will play twice daily for 10 days, and researchers will measure changes in pain intensity and quality.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
virtual reality walking game
What this could lead to
If it works, this could offer a drug-free way to reduce chronic nerve pain after spinal cord injury, improving daily life without medication side effects.
What could go wrong
This is an early-stage trial testing a behavioral intervention, so results may not be strong or lasting. The effect may vary by individual, and the VR setup might not be comfortable for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 250 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2021

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: The study will recruit individuals with complete injury (American Spinal Injury Association \[ASIA\] classification A) with lumbar, paraplegic, or low tetraplegic (C5-C7) injury. Additional criteria will include: 1. Must have persistent NP symptoms that are of daily severity of at least 4/10 for 3 or more months 2. Must endorse more than 2 items on a 7-item Spinal Cord Injury Pain Instrument, SCIPI 3. Must be 18 years of age or older 4. Must be more than one year post-injury to begin study (can be screened at an earlier time for eligibility) 5. Must have mobile connectivity with usable service 6. Must be stable on pain medication for 1 or more months 7. Must be cleared on the VRWalk physical activity clearance scale 8. Must not have motion sickness that interferes with daily life Exclusion Criteria: 1. Individuals with Injury levels between C1 and C4 2. Individuals under the age of 18 3. Individuals who were injured within the past year 4. Individuals who cannot comprehend spoken English 5. Individuals who are in prison 6. Individuals who are blind 7. Individuals who experience severe motion sickness

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Conditions

The condition(s) this trial relates to.

neuralgia spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neuropathic pain Spinal cord injuries

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Texas A&M University

    RECRUITING

    College Station, Texas, 77843, United States

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35294, United States

  • University of New South Wales

    COMPLETED

    Sydney, New South Wales, Australia

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