Coconut oil takes on chlorhexidine in gum disease showdown
NCT ID NCT07706387
First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time
Summary
This study compares virgin coconut oil mouthwash to the standard chlorhexidine mouthwash as an add-on to deep cleaning for people with stage II periodontitis (gum disease). Over 30 days, researchers measure gum health indicators like pocket depth, bleeding, and inflammation. They also check levels of a key inflammatory marker in gum fluid to see which mouthwash works better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- virgin coconut oil mouthwash and chlorhexidine mouthwash
- What this could lead to
- If effective, virgin coconut oil could offer a natural, affordable alternative to standard mouthwash for managing gum disease.
- What could go wrong
- This is a small, early-stage trial with only 42 participants, so results may not apply to everyone. The study does not test long-term safety or effectiveness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 42 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 1\. Both genders. 2. Age (30-50) years old. 3. Systemically free according to the modified Burkett's health history questionnaire . 4\. Generalized Periodontitis Stage II . 5. Having at least 20 tooth excluding wisdoms. 6. No history of dental visit in past three months. 7. Participants willing to commit for the entire period of the trial and agreed to sign the written consent after full explanation of the study. Exclusion Criteria: * 1\. Smokers. 2. Status of Pregnancy or Contraceptives usage. 3. Allergy to coconut oil . 4. Previous Periodontal treatment within the last 6 months. 5. Antibiotic and/or Anti-inflammatory therapy within the last 6 months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Faculty of Dentistry,Ain Shams University
Cairo, Cairo Governorate, 11566, Egypt
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