A tiny camera could make gum surgery more precise
NCT ID NCT05275192
First seen Aug 17, 2026 · Last updated Aug 18, 2026 · Updated 1 time
Summary
This pilot study tests whether using a videoscope—a small camera that gives surgeons a magnified, clearer view—during minimally invasive gum surgery improves outcomes for people with severe chronic periodontitis. Participants are randomly assigned to receive surgery with the videoscope, standard minimally invasive surgery, or conventional guided tissue regeneration. The study measures changes in gum attachment, pocket depth, and bone fill over 12 months to see if better visualization leads to more predictable regeneration of the tissues supporting the teeth.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Videoscope-assisted minimally invasive surgery for periodontal regeneration
- What this could lead to
- If successful, this could make gum-regeneration surgery more predictable, potentially saving more teeth affected by severe gum disease.
- What could go wrong
- This is a small pilot study, so results may not apply broadly. The videoscope may not improve outcomes enough to justify its use, and surgery carries standard risks like infection or swelling.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2022
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * • Individual must be between the age of 18 and 70 years of age * ASA I or II systemically healthy subjects * Individuals presenting with at least 1 single or multirooted tooth with residual, isolated, interproximal bony defect with probing depths (PD) ≥ 6 mm, clinical attachment loss (CAL) ≥ 6mm, bleeding upon probing (BOP), and ≥ 2mm width of attached gingiva (WAG) * Radiographic evidence of interproximal alveolar bone loss, on existing (\< 2 years old) dental radiographs of diagnostic quality taken at the COD * Vital tooth or previous root canal therapy with no signs/symptoms of pathology * Individuals with plaque scores ≤ 20% * English speaking subjects (Individual must be willing to follow all the study requirements and participate in the study procedures in its entirety and read, understand the informed consent form) Exclusion Criteria: * Individuals not referred from the Predoctoral Periodontics Student Clinics * Uncontrolled systemic disorders such as hypertension, heart disease, bleeding disorders, metabolic bone diseases, autoimmune disorders, etc., that may influence cellular/healing status * Diabetics * Current smokers * Individual less than 18 years of age * Individuals with non-isolated, interproximal PD ≥ 4 mm extending to the facial/buccal and/or palatal/lingual tooth surfaces * Teeth with Grade 2 or 3 mobility * Teeth with metal restorations such as a porcelain fused to metal crown (due to scattering of radiographic images) * Intrabony defects on dental implants * Individual who take medications known to affect host immunity or periodontal tissues (ex. steroids, antibiotics, phenytoin, etc.) in the previous 6 months * Individuals on chronic anti-platelet/anti-coagulant therapy * Oral pathologies other than periodontal disease (ex. periapical lesions of non-periodontal origin) * Subjects who may be pregnant based on a positive pregnancy test * Non-English speaking individuals
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Illinois, Chicago, College of Dentistry, Periodontics
Chicago, Illinois, 60612, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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