New hope for lupus patients: experimental drug targets kidney damage
NCT ID NCT05201469
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 21 times
Summary
This study tests an experimental drug called VIB4920 for people with active lupus nephritis, a serious kidney complication of lupus. About 74 adults will receive either VIB4920 or a placebo, along with standard medications (mycophenolate mofetil and prednisone). The main goal is to see if VIB4920 helps achieve complete kidney response by 36 weeks, meaning less protein in urine and stable kidney function.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Columbia University Medical Center: Department of Medicine, Division of Rheumatology
RECRUITINGNew York, New York, 10032, United States
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Emory University School of Medicine: Division of Rheumatology
RECRUITINGAtlanta, Georgia, 30307, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Feinstein Institute for Medical Research: Center for Autoimmune and Musculoskeletal Diseases
RECRUITINGManhasset, New York, 11030, United States
Contact Email: •••••@•••••
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital for Special Surgery, New York: Division of Rheumatology
NOT_YET_RECRUITINGNew York, New York, 10021, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Penn State Health Milton S. Hershey Medical Center: Division of Rheumatology
RECRUITINGHershey, Pennsylvania, 17033, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Temple University, Lewis Katz School of Medicine, Department of Medicine: Nephrology
RECRUITINGPhiladelphia, Pennsylvania, 19140, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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UCLA Medical Center: Division of Rheumatology
RECRUITINGLos Angeles, California, 90095, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California San Diego School of Medicine: Division of Rheumatology, Allergy and Immunology
RECRUITINGLa Jolla, California, 92093, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California San Francisco School of Medicine: Lupus Clinic and Rheumatology Clinical Research Center
RECRUITINGSan Francisco, California, 94143, United States
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University of Chicago, Department of Medicine: Rheumatology
RECRUITINGChicago, Illinois, 60637, United States
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University of Colorado School of Medicine: Division of Rheumatology
RECRUITINGAurora, Colorado, 80045, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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University of Miami Miller School of Medicine: Nephrology & Hypertension Division
RECRUITINGMiami, Florida, 33136, United States
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
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University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
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Washington University School of Medicine in St. Louis: Division of Nephrology
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yale University School of Medicine: Section of Rheumatology
RECRUITINGNew Haven, Connecticut, 06519, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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of California, Irvine School of Medicine Division of Rheumatology
RECRUITINGOrange, California, 92868, United States
Contact Email: •••••@•••••
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Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.