Promising combo targets tough leukemia in early trial
NCT ID NCT03504644
First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 2 times
Summary
This study tests a combination of two drugs—venetoclax and vincristine—in people with T-cell or B-cell acute lymphoblastic leukemia that has returned or not responded to prior treatment. The goal is to find the safest dose and see if the combo can lead to remission. About 40 adults will take part in this early-phase trial.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1/2
Runs two stages together: safety and dose first, then whether the treatment works.
- Participants
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40 people
The number who actually took part.
- Started
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Aug 2018
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 0: Patient must be considered a potential candidate for the trial * NOTE: Enrollment to Step 0 may occur prior to or following completion of the assessments to verify patient eligibility for Step 1 registration; bone marrow and/or peripheral blood specimens collected during Step 0 or prior to treatment on Step 1 must be submitted for central review in order for the patient to be considered evaluable; results will not be reported to the site and will not impact patient participation in the trial * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Patients must have a diagnosis of: * Relapsed or refractory B-cell or T-cell ALL after multi-agent chemotherapy * Patients with \< 5% blasts may enroll on trial in phase I portion provided that minimal residual disease (MRD) is present at \> 10\^-3 as tested on an assay with minimum sensitivity of 10\^-4 OR * Relapsed lymphoblastic lymphoma * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C): Age \>= 18 years * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Eastern Cooperative Oncology Group (ECOG) performance status 0-2 * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Adequate liver function with aspartate aminotransferase (AST)/alanine aminotransferase (ALT) less than 3 x upper limit of normal and total bilirubin less than 2 mg/dL within 10 days prior to first dose of study agent * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Circulating white blood cell (WBC) count must not be above 25 x 10\^9/L at the time of registration * Patients with WBC count above 25 x 10\^9/L are eligible if they have started steroids or hydroxyurea per institutional guidelines * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Glomerular filtration rate (GFR) of at least 40 mL/min within 7 days prior to first dose of study agent * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: All patients of childbearing potential must have a blood test or urine study with a minimum sensitivity 25 IU/L or equivalent units of human chorionic gonadotropin (HCG) within 2 weeks prior to registration to rule out pregnancy * A patient of childbearing potential is defined as anyone, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has achieved menarche at some point, 2) has not undergone a hysterectomy or bilateral oophorectomy; or 3) has not been naturally postmenopausal for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months) * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Patients must not expect to conceive or father children by using accepted and highly effective method(s) of contraception or by abstaining from sexual intercourse for the duration of their participation in the study and for 30 days after the last dose of venetoclax * Should a patient or a partner of a patient become pregnant or suspect they are pregnant while participating in the study, the treating physician should be notified immediately * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: No evidence of prior solid malignancy except adequately treated non-melanoma skin cancer, in situ cervical carcinoma, or any surgically- or radiation-cured malignancy continuously disease free for \>= 2 years so as not to interfere with interpretation of radiographic response * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Patients may be enrolled with a prior allogeneic hematopoietic stem cell transplant (HSCT) but the transplant date must be at least 90 days before date of registration to step 1; patient must be off immunosuppression and without active graft versus host disease (GVHD) prior to registration to step 1 if previous HSCT * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 0: Patient must be considered a potential candidate for the trial * NOTE: Enrollment to Step 0 may occur prior to or following completion of the assessments to verify patient eligibility for Step 1 registration * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Relapsed or refractory B-cell or T-cell ALL, including lymphoblastic lymphoma, after at least one line of chemotherapy * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Age \>= 18 years * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: ECOG performance status 0-2 * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Adequate liver function with AST/ALT less than 3 x upper limit of normal and total bilirubin less than 2 mg/dL within 10 days prior to first dose of study agent * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Circulating WBC count must not be above 25 x 10\^9/L at the time of registration to step 1 * Patients with WBC count above 25 x 10\^9/L are eligible if they have started steroids or hydroxyurea per institutional guidelines * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: GFR of at least 40 mL/min within 7 days prior to first dose of study agent * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: All patients of childbearing potential must have a blood test or urine study with a minimum sensitivity 25 IU/L or equivalent units of HCG within 2 weeks prior to registration to rule out pregnancy. * A patient of childbearing potential is defined as anyone, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has achieved menarche at some point, 2) has not undergone a hysterectomy or bilateral oophorectomy; or 3) has not been naturally postmenopausal for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months) * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Patients must not expect to conceive or father children by using accepted and highly effective method(s) of contraception or by abstaining from sexual intercourse for the duration of their participation in the study and for 30 days after the last dose of venetoclax * Should a patient or partner of a patient become pregnant or suspect she is pregnant while participating in this study, the treating physician should be informed immediately * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Patients may be enrolled with a prior allogeneic hematopoietic stem cell transplant (HSCT) but the transplant date must be at least 90 days before date of enrollment; patient must be off immunosuppression and without active GVHD prior to enrollment if previous HSCT. Low-dose steroids (10mg or less) are allowed Exclusion Criteria: * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Patients of childbearing potential must not be pregnant or breast-feeding due to risk of fetal harm by the chemotherapeutic agents prescribed in this protocol * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Patients with isolated testicular or central nervous system (CNS) relapsed disease are not eligible * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Patients must not have Burkitt's lymphoma/leukemia based on the World Health Organization (WHO) criteria * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Patients must not have active central nervous system (CNS) leukemia, as defined by unequivocal morphologic evidence of lymphoblasts in the cerebrospinal fluid (CSF) or the use of CNS-directed local treatment for active disease within the prior 28 days; prophylactic intrathecal chemotherapy is allowed; previously treated CNS disease with documented clearance of the CSF will be allowed * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Patients will not be enrolled if they received prior chemotherapy within 2 weeks before registration to step 1 with the following exceptions: to reduce the circulating lymphoblast count or palliation or for ALL maintenance (mercaptopurine, methotrexate, vincristine, thioguanine, and/or tyrosine kinase inhibitors) * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Patients cannot have poorly controlled chronic viral infections including hepatitis B, C, or human immunodeficiency virus (HIV); HIV positive patients are allowed on this study if they have a CD4 count \>= 400, and are on a stable antiviral regimen * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Patients with New York Heart Association (NYHA) class III or IV heart failure, uncontrolled angina, severe uncontrolled ventricular arrhythmias, or electrocardiographic evidence of acute ischemia may not be enrolled * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Patients with serious medical or psychiatric illness that in the opinion of the primary investigator is likely to interfere with study participation may not be enrolled * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Patients must not be taking any other experimental medications within 21 days prior to registration. Clinical trial medications that are Food and Drug Administration (FDA) approved will be allowed within 14 days prior to registration * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Patients should not have received the following within 7 days prior to the first dose of study drug: * Strong and moderate CYP3A inhibitors; * Strong and moderate CYP3A inducers * ELIGIBILITY CRITERIA - PHASE I (ARMS A, B, C) - STEP 1: Patients must not have grade 3 or higher peripheral neuropathy or history of grade 3 or higher peripheral neuropathy. Patients with familial demyelinating disease like Charcot-Marie-Tooth disease are also excluded * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Patients with prior venetoclax treatment for ALL will be excluded * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Patients must not be pregnant or breast-feeding due to risk of fetal harm by the chemotherapeutic agents prescribed in this protocol * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: No evidence of prior malignancy except adequately treated non-melanoma skin cancer, in situ cervical or breast carcinoma, or chemotherapy-surgically- or radiation-cured malignancy continuously disease free for \>= 2 years * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Patients with isolated testicular or CNS relapsed disease are not eligible * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Patients must not have Burkitt's lymphoma/leukemia based on the WHO criteria * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Patients must not have active central nervous system (CNS) leukemia, as defined by unequivocal morphologic evidence of lymphoblasts in the cerebrospinal fluid (CSF) or the use of CNS-directed local treatment for active disease within the prior 28 days; prophylactic intrathecal chemotherapy is allowed; previously treated CNS disease with documented clearance of the CSF will be allowed and once cleared, prophylactic intrathecal chemotherapy can be continued * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Patient will not be enrolled if they received prior chemotherapy within 2 weeks before enrollment with the following exceptions: to reduce the circulating lymphoblast count or palliation (i.e., steroids or hydroxyurea), for ALL maintenance (mercaptopurine, methotrexate, vincristine, thioguanine, and/or tyrosine kinase inhibitors) * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Patients cannot have poorly controlled chronic viral infections including hepatitis B, C, or HIV; HIV positive patients with undetectable viral load are allowed * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Patients with NYHA class III or IV heart failure, uncontrolled angina, severe uncontrolled ventricular arrhythmias, or electrocardiographic evidence of acute ischemia may not be enrolled * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Patients with serious medical or psychiatric illness that in the opinion of the primary investigator is likely to interfere with study participation may not be enrolled * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Patients must not be participating in any other clinical trial or taking any other experimental medications within 21 days prior to registration * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Patients must not have received the following within 7 days prior to the first dose of study drug or while on study treatment: * Strong and moderate CYP3A inhibitors; * Strong and moderate CYP3A inducers * ELIGIBILITY CRITERIA - PHASE II (ARM D) - STEP 1: Patients must not have grade 3 or higher peripheral neuropathy or history of grade 3 peripheral neuropathy; patients with familial demyelinating diseases like Charcot-Marie-Tooth disease also excluded
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Abbott-Northwestern Hospital
Minneapolis, Minnesota, 55407, United States
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Alaska Breast Care and Surgery LLC
Anchorage, Alaska, 99508, United States
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Alaska Oncology and Hematology LLC
Anchorage, Alaska, 99508, United States
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Alaska Women's Cancer Care
Anchorage, Alaska, 99508, United States
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Anchorage Associates in Radiation Medicine
Anchorage, Alaska, 98508, United States
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Anchorage Oncology Centre
Anchorage, Alaska, 99508, United States
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Anchorage Radiation Therapy Center
Anchorage, Alaska, 99504, United States
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BJC Outpatient Center at Sunset Hills
Sunset Hills, Missouri, 63127, United States
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Bay Area Hospital
Coos Bay, Oregon, 97420, United States
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CARTI Cancer Center
Little Rock, Arkansas, 72205, United States
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Cambridge Medical Center
Cambridge, Minnesota, 55008, United States
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Cancer Care Center of O'Fallon
O'Fallon, Illinois, 62269, United States
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Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois, 62526, United States
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Cancer Center of Western Wisconsin
New Richmond, Wisconsin, 54017, United States
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Cancer Center-Metro Medical Center Bayamon
Bayamón, 00959-5060, Puerto Rico
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Central Care Cancer Center - Bolivar
Bolivar, Missouri, 65613, United States
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Central Care Cancer Center - Garden City
Garden City, Kansas, 67846, United States
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Central Care Cancer Center - Great Bend
Great Bend, Kansas, 67530, United States
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Centralia Oncology Clinic
Centralia, Illinois, 62801, United States
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Centro Comprensivo de Cancer de UPR
San Juan, 00927, Puerto Rico
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Clackamas Radiation Oncology Center
Clackamas, Oregon, 97015, United States
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Community Medical Center
Toms River, New Jersey, 08755, United States
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Cox Cancer Center Branson
Branson, Missouri, 65616, United States
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CoxHealth South Hospital
Springfield, Missouri, 65807, United States
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Crossroads Cancer Center
Effingham, Illinois, 62401, United States
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Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
Lebanon, New Hampshire, 03756, United States
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Decatur Memorial Hospital
Decatur, Illinois, 62526, United States
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Delbert Day Cancer Institute at PCRMC
Rolla, Missouri, 65401, United States
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Doctors Cancer Center
Manati, 00674, Puerto Rico
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Fairview Clinics and Surgery Center Maple Grove
Maple Grove, Minnesota, 55369, United States
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Fairview Lakes Medical Center
Wyoming, Minnesota, 55092, United States
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Fairview Northland Medical Center
Princeton, Minnesota, 55371, United States
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Fairview Ridges Hospital
Burnsville, Minnesota, 55337, United States
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Fairview Southdale Hospital
Edina, Minnesota, 55435, United States
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Freeman Health System
Joplin, Missouri, 64804, United States
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Good Samaritan Regional Health Center
Mount Vernon, Illinois, 62864, United States
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HSHS Saint Elizabeth's Hospital
O'Fallon, Illinois, 62269, United States
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Health Partners Inc
Minneapolis, Minnesota, 55454, United States
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Heartland Regional Medical Center
Saint Joseph, Missouri, 64506, United States
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Hennepin County Medical Center
Minneapolis, Minnesota, 55415, United States
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Houston Methodist Hospital
Houston, Texas, 77030, United States
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Illinois CancerCare - Washington
Washington, Illinois, 61571, United States
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Illinois CancerCare-Bloomington
Bloomington, Illinois, 61704, United States
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Illinois CancerCare-Canton
Canton, Illinois, 61520, United States
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Illinois CancerCare-Carthage
Carthage, Illinois, 62321, United States
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Illinois CancerCare-Dixon
Dixon, Illinois, 61021, United States
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Illinois CancerCare-Eureka
Eureka, Illinois, 61530, United States
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Illinois CancerCare-Galesburg
Galesburg, Illinois, 61401, United States
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Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois, 61443, United States
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Illinois CancerCare-Macomb
Macomb, Illinois, 61455, United States
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Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois, 61350, United States
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Illinois CancerCare-Pekin
Pekin, Illinois, 61554, United States
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Illinois CancerCare-Peoria
Peoria, Illinois, 61615, United States
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Illinois CancerCare-Peru
Peru, Illinois, 61354, United States
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Illinois CancerCare-Princeton
Princeton, Illinois, 61356, United States
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John H Stroger Jr Hospital of Cook County
Chicago, Illinois, 60612, United States
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Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287, United States
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Kadlec Clinic Hematology and Oncology
Kennewick, Washington, 99336, United States
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Katmai Oncology Group
Anchorage, Alaska, 99508, United States
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Lake Regional Hospital
Osage Beach, Missouri, 65065, United States
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Lakeview Hospital
Stillwater, Minnesota, 55082, United States
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Loyola Center for Health at Burr Ridge
Burr Ridge, Illinois, 60527, United States
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Loyola Medicine Homer Glen
Homer Glen, Illinois, 60491, United States
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Loyola University Medical Center
Maywood, Illinois, 60153, United States
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MU Health Care Goldschmidt Cancer Center
Jefferson City, Missouri, 65109, United States
-
Marjorie Weinberg Cancer Center at Loyola-Gottlieb
Melrose Park, Illinois, 60160, United States
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Marshfield Clinic-Minocqua Center
Minocqua, Wisconsin, 54548, United States
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Marshfield Medical Center - Weston
Weston, Wisconsin, 54476, United States
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Marshfield Medical Center-EC Cancer Center
Eau Claire, Wisconsin, 54701, United States
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Marshfield Medical Center-Marshfield
Marshfield, Wisconsin, 54449, United States
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Marshfield Medical Center-Rice Lake
Rice Lake, Wisconsin, 54868, United States
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Marshfield Medical Center-River Region at Stevens Point
Stevens Point, Wisconsin, 54482, United States
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Mayo Clinic Hospital in Arizona
Phoenix, Arizona, 85054, United States
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Mayo Clinic in Arizona
Scottsdale, Arizona, 85259, United States
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Mayo Clinic in Florida
Jacksonville, Florida, 32224-9980, United States
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Memorial Hospital of Carbondale
Carbondale, Illinois, 62902, United States
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Memorial Medical Center
Springfield, Illinois, 62781, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Mercy Clinic-Rolla-Cancer and Hematology
Rolla, Missouri, 65401, United States
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Mercy Hospital
Coon Rapids, Minnesota, 55433, United States
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Mercy Hospital Fort Smith
Fort Smith, Arkansas, 72903, United States
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Mercy Hospital Joplin
Joplin, Missouri, 64804, United States
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Mercy Hospital Oklahoma City
Oklahoma City, Oklahoma, 73120, United States
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Mercy Hospital Saint Louis
St Louis, Missouri, 63141, United States
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Mercy Hospital South
St Louis, Missouri, 63128, United States
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Mercy Hospital Springfield
Springfield, Missouri, 65804, United States
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Mercy Hospital Washington
Washington, Missouri, 63090, United States
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Methodist Medical Center of Illinois
Peoria, Illinois, 61636, United States
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Minnesota Oncology - Burnsville
Burnsville, Minnesota, 55337, United States
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Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota, 55109, United States
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Minnesota Oncology Hematology PA-Woodbury
Woodbury, Minnesota, 55125, United States
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Missouri Baptist Medical Center
St Louis, Missouri, 63131, United States
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Missouri Baptist Sullivan Hospital
Sullivan, Missouri, 63080, United States
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Monmouth Medical Center
Long Branch, New Jersey, 07740, United States
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Monticello Cancer Center
Monticello, Minnesota, 55362, United States
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New Ulm Medical Center
New Ulm, Minnesota, 56073, United States
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North Memorial Medical Health Center
Robbinsdale, Minnesota, 55422, United States
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Northwestern University
Chicago, Illinois, 60611, United States
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OSF Saint Francis Medical Center
Peoria, Illinois, 61637, United States
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OSF Saint Francis Radiation Oncology at Pekin
Pekin, Illinois, 61554, United States
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OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Peoria, Illinois, 61615, United States
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PROncology
San Juan, 00927, Puerto Rico
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Pacific Gynecology Specialists
Seattle, Washington, 98104, United States
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Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota, 55416, United States
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Parkland Health Center - Farmington
Farmington, Missouri, 63640, United States
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PeaceHealth Saint John Medical Center
Longview, Washington, 98632, United States
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PeaceHealth Saint Joseph Medical Center
Bellingham, Washington, 98225, United States
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PeaceHealth Southwest Medical Center
Vancouver, Washington, 98664, United States
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PeaceHealth United General Medical Center
Sedro-Woolley, Washington, 98284, United States
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Penn State Milton S Hershey Medical Center
Hershey, Pennsylvania, 17033-0850, United States
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Providence Alaska Medical Center
Anchorage, Alaska, 99508, United States
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Providence Cancer Institute Clackamas Clinic
Clackamas, Oregon, 97015, United States
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Providence Newberg Medical Center
Newberg, Oregon, 97132, United States
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Providence Portland Medical Center
Portland, Oregon, 97213, United States
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Providence Regional Cancer Partnership
Everett, Washington, 98201, United States
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Providence Regional Cancer System-Aberdeen
Aberdeen, Washington, 98520, United States
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Providence Regional Cancer System-Centralia
Centralia, Washington, 98531, United States
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Providence Regional Cancer System-Lacey
Lacey, Washington, 98503, United States
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Providence Regional Cancer System-Shelton
Shelton, Washington, 98584, United States
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Providence Regional Cancer System-Yelm
Yelm, Washington, 98597, United States
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Providence Saint Joseph Medical Center/Disney Family Cancer Center
Burbank, California, 91505, United States
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Providence Saint Mary Regional Cancer Center
Walla Walla, Washington, 99362, United States
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Providence Saint Vincent Medical Center
Portland, Oregon, 97225, United States
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Puerto Rico Hematology Oncology Group
Bayamón, 00961, Puerto Rico
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Regions Hospital
Saint Paul, Minnesota, 55101, United States
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Rice Memorial Hospital
Willmar, Minnesota, 56201, United States
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Ridgeview Medical Center
Waconia, Minnesota, 55387, United States
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Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08903, United States
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SIH Cancer Institute
Carterville, Illinois, 62918, United States
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Saint Anthony's Health
Alton, Illinois, 62002, United States
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Saint Charles Health System
Bend, Oregon, 97701, United States
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Saint Charles Health System-Redmond
Redmond, Oregon, 97756, United States
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Saint Francis Cancer Center
Greenville, South Carolina, 29607, United States
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Saint Francis Hospital
Greenville, South Carolina, 29601, United States
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Saint Francis Medical Center
Cape Girardeau, Missouri, 63703, United States
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Saint Francis Regional Medical Center
Shakopee, Minnesota, 55379, United States
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Saint John's Hospital - Healtheast
Maplewood, Minnesota, 55109, United States
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Saint Louis Cancer and Breast Institute-Ballwin
Ballwin, Missouri, 63011, United States
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Saint Louis Cancer and Breast Institute-South City
St Louis, Missouri, 63109, United States
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Saint Luke's Cancer Institute - Boise
Boise, Idaho, 83712, United States
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Saint Luke's Cancer Institute - Fruitland
Fruitland, Idaho, 83619, United States
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Saint Luke's Cancer Institute - Meridian
Meridian, Idaho, 83642, United States
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Saint Luke's Cancer Institute - Nampa
Nampa, Idaho, 83686, United States
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Saint Luke's Cancer Institute - Twin Falls
Twin Falls, Idaho, 83301, United States
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Saint Mary's Hospital
Centralia, Illinois, 62801, United States
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Saint Patrick Hospital - Community Hospital
Missoula, Montana, 59802, United States
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Sainte Genevieve County Memorial Hospital
Sainte Genevieve, Missouri, 63670, United States
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San Juan City Hospital
San Juan, 00936, Puerto Rico
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San Juan Community Oncology Group
San Juan, 00917, Puerto Rico
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Smilow Cancer Center/Yale-New Haven Hospital
New Haven, Connecticut, 06510, United States
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Smilow Cancer Hospital Care Center at Saint Francis
Hartford, Connecticut, 06105, United States
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Southeast Cancer Center
Cape Girardeau, Missouri, 63703, United States
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Southern Illinois University School of Medicine
Springfield, Illinois, 62702, United States
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Springfield Clinic
Springfield, Illinois, 62702, United States
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Swedish Cancer Institute-Edmonds
Edmonds, Washington, 98026, United States
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Swedish Cancer Institute-Issaquah
Issaquah, Washington, 98029, United States
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Swedish Medical Center-Ballard Campus
Seattle, Washington, 98107, United States
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Swedish Medical Center-Cherry Hill
Seattle, Washington, 98122-5711, United States
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Swedish Medical Center-First Hill
Seattle, Washington, 98122, United States
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Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107, United States
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United Hospital
Saint Paul, Minnesota, 55102, United States
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Unity Hospital
Fridley, Minnesota, 55432, United States
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University of Florida Health Science Center - Jacksonville
Jacksonville, Florida, 32209, United States
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University of New Mexico Cancer Center
Albuquerque, New Mexico, 87106, United States
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University of Pennsylvania/Abramson Cancer Center
Philadelphia, Pennsylvania, 19104, United States
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Valley Radiation Oncology
Peru, Illinois, 61354, United States
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Western Illinois Cancer Treatment Center
Galesburg, Illinois, 61401, United States
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Yale University
New Haven, Connecticut, 06520, United States
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