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New combo therapy shows promise for Tough-to-Treat leukemia

NCT ID NCT02879695

First seen May 16, 2026 · Last updated May 24, 2026 · Updated 3 times

Summary

This early-stage study tests a combination of three immunotherapy drugs (blinatumomab, nivolumab, and ipilimumab) in adults with a type of leukemia that has returned or not responded to standard treatment. The main goals are to find the safest dose and identify side effects. About 28 participants will receive the drugs to see if the combination can help the immune system fight the cancer more effectively.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Huntsman Cancer Institute/University of Utah

    Salt Lake City, Utah, 84112, United States

  • Johns Hopkins University/Sidney Kimmel Cancer Center

    Baltimore, Maryland, 21287, United States

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • University of Kentucky/Markey Cancer Center

    Lexington, Kentucky, 40536, United States

  • University of Pittsburgh Cancer Institute (UPCI)

    Pittsburgh, Pennsylvania, 15232, United States

  • Yale University

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.