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New drug shows promise for rare movement disorder

NCT ID NCT04577352

First seen Apr 09, 2026 · Last updated May 24, 2026 · Updated 7 times

Summary

This study tested an experimental drug called vatiquinone in 146 people with Friedreich ataxia, a rare disease that affects movement and coordination. Participants took the drug or a placebo for 72 weeks to see if it slowed worsening of symptoms, measured by a standard rating scale. The trial is now complete, and results help researchers understand whether vatiquinone can help control this progressive condition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CBR Neurogenetic Research Clinic, University of Auckland

    Auckland, 1023, New Zealand

  • CHU Sainte-Justine

    Montreal, Quebec, H3T1C5, Canada

  • Centre de Recherche du Centre Hospitalier de l'Université de Montreal (CRCHUM)

    Montreal, Quebec, H2X 0A9, Canada

  • Department of Neurology and Hertie-Institute for Clinical Brain Research German Center of Neurodegenerative Diseases (DZNE)

    Tübingen, 72076, Germany

  • Hospital Sant Joan de Déu Barcelona Unidad de Enfermedades Neuromusculares

    Barcelona, 08950, Spain

  • Hôpital Pitié-Salpêtrière, Institut du Cerveau (Paris Brain Institute)

    Paris, 75646, France

  • Murdoch Children's Research Institute

    Parkville, Victoria, 3052, Australia

  • Ospedale Pediatrico Bambino Gesu' IRCCS

    Roma, 00165, Italy

  • The Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • UCLA

    Los Angeles, California, 90095, United States

  • University of Campinas (UNICAMP) - School of Medical Sciences, Dept of Neurology

    São Paulo, 13083-887, Brazil

  • University of Florida

    Gainesville, Florida, 32608, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • University of South Florida

    Tampa, Florida, 33612, United States

Conditions

Explore the condition pages connected to this study.