Scientists hunt for genetic warning signs of deadly artery spasm after brain bleed
NCT ID NCT01779713
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aimed to find genetic markers that could predict which patients will develop vasospasm—a dangerous narrowing of brain arteries—after a bleeding brain aneurysm. Researchers collected blood samples daily from 89 patients for 12 days to analyze their DNA and RNA. The goal is to better understand why some patients develop this complication and eventually help doctors personalize treatment to reduce risk.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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89 people
The number who actually took part.
- Started
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Feb 2013
- Finished
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Aug 2016
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Caucasian subjects, aged more than 18, suffering of sub-arachnoid hemorrhage
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient entering the neurosurgical unit in the 48 hours following an aneurismal sub-arachnoid hemorrhage and treated in the 96 first hours (embolization or surgery) * Aged more than 18 * Caucasian origin * Affiliated to a social care service * Having (or one of is related if he is comatose) given its informed consent Exclusion Criteria: * Subjects which do not have a social care protection * Subjects (or one of is related if he is comatose) refusing to sign the consent * Subjects being under a protective juridical system for adults
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Neuro-anesthesia intensive care unit, Pitié-Salpétrière hospital
Paris, 75013, France
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Other studies related to the condition(s) this trial covers.
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