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Spine surgery infection fighter: could a sprinkle of antibiotic powder be the answer?

NCT ID NCT03839914

First seen Apr 30, 2026 · Last updated Jun 22, 2026 · Updated 11 times

Summary

This study tests whether placing vancomycin powder directly into the surgical wound before closing it can prevent infections after open spine surgery. The trial includes 76 adults at high risk for infection due to spinal deformity, trauma, or tumor. Half receive the powder plus standard care, the other half standard care alone, and researchers track infection rates and side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Queen Mary Hospital

    Hong Kong, Hong Kong

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

vancomycin powder

What this could lead to

If it works, this could provide a simple, low-cost way to reduce surgical site infections in high-risk spine surgery patients.

What could go wrong

This is a small, early-stage trial with only 76 participants, so results may not apply to everyone. Vancomycin can cause kidney problems or allergic reactions.

Conditions

The condition(s) this trial relates to.

injury spinal cord cancer spinal cord neoplasm spinal injury Surgical Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.