Simpler dosing for MRSA may be just as effective, major trial tests
NCT ID NCT04793152
First seen Jan 24, 2026 · Last updated May 23, 2026 · Updated 14 times
Summary
This study tests whether a simpler way of dosing the antibiotic vancomycin works as well as the more complex method for serious MRSA infections. About 700 adults with infections like bloodstream, lung, or bone infections will be randomly assigned to one of two dosing strategies. The goal is to see if targeting a trough level of 10-15 mg/L is non-inferior to targeting an AUC/MIC of 400-600, with treatment failure measured at 90 days.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
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Contact
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Locations
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Hamilton Health Sciences
RECRUITINGHamilton, Ontario, L8L 2X2, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Kingston Health Sciences Centre
RECRUITINGKingston, Ontario, K7L 2V7, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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McGill University Health Centre
RECRUITINGMontreal, Quebec, H3H 2R9, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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St. Joseph's Healthcare Hamilton
RECRUITINGHamilton, Ontario, L8N 4A6, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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