Could a common mood stabilizer help beat colorectal cancer?
NCT ID NCT06714357
First seen Oct 01, 2025 · Last updated May 20, 2026 · Updated 32 times
Summary
This study tests whether adding valproic acid (a drug used for seizures and mood disorders) to a standard anti-EGFR therapy can help people with advanced colorectal cancer whose cancer has returned after previous treatments. About 130 adults with a specific genetic type (RAS/BRAF wild-type) will be randomly assigned to receive the combination or standard care alone. The goal is to see if the combination delays cancer growth and to understand how resistance develops.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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AORN San Giuseppe Moscati Avellino
ACTIVE_NOT_RECRUITINGAvellino, Italy, Italy
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AORN Sant'Anna e San Sebastiano
RECRUITINGCaserta, CE, Italy
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Azienda Sanitaria Universitaria Friuli Centrale
NOT_YET_RECRUITINGUdine, Italy, Italy
Contact
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Istituto Nazionale Tumori IRCCS Fondazione G. Pascale
RECRUITINGNaples, Napoli, 80131, Italy
Contact
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Ospedale Civile San Giovanni di Dio
NOT_YET_RECRUITINGFrattamaggiore, Napoli, Italy
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Pia Fondazione Di Culto E Religione Card G Panico
NOT_YET_RECRUITINGTricase, Lecce, Italy
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Presidio Ospedaliero "Santa Maria delle Grazie"
NOT_YET_RECRUITINGPozzuoli, PZ, Italy
Contact
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Università degli studi della Campania Luigi Vanvitelli
RECRUITINGNaples, Italia, Italy
Contact
Conditions
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