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Eye scan could spot hidden nerve pain in dry eye sufferers

NCT ID NCT05653921

First seen Jan 11, 2026 · Last updated May 25, 2026 · Updated 21 times

Summary

This study aims to see if a special microscope scan (called IVCM) can reliably detect tiny nerve growths (microneuromas) that cause neuropathic corneal pain—a severe type of dry eye. Researchers will scan the eyes of 438 adults with dry eye symptoms to confirm whether these nerve findings are consistent over time. The goal is to establish a clear, non-invasive way to diagnose this painful condition.

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Contacts and locations

Locations

  • Scheie Eye Institute, University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Tufts Medical Center

    Boston, Massachusetts, 02111, United States

Conditions

Explore the condition pages connected to this study.