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Neck therapy may soothe IBS symptoms, small study hopes

NCT ID NCT07560345

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a series of gentle, passive neck movements (called neurodynamic mobilization of the vagus nerve) can reduce symptoms of irritable bowel syndrome (IBS) in women. Thirty-two women aged 20-45 with mild to moderate IBS will receive the treatment for 6 weeks. Researchers will measure changes in symptom severity and quality of life before and after the intervention.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
neurodynamic mobilization of vagus nerve (a series of passive neck movements)
What this could lead to
If it works, this could offer a non-drug, hands-on approach to reduce IBS symptoms and improve quality of life in women.
What could go wrong
This is a very small, early-stage study with only 32 women, so results may not apply to everyone. The treatment is experimental and may not provide significant relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 32 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 45 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 32 Females with mild to moderate IBS ,were recruited for this study by referral from a physician. * aged 20-45 (i.e., the most common age for developing IBS) * Patients must experience abdominal pain recurring at least once weekly over the past three months. * This pain must be linked to two or more of the following features: occurring in relation to defecation, accompanied by a change in stool frequency, or accompanied by a change in stool form or appearance. * Symptoms should have been present during the last three months, with onset at least six months before diagnosis. Exclusion Criteria: Subjects will be excluded if they have: * Organic gastrointestinal disorders. * Thyroid abnormalities. * Coexisting cardiovascular, respiratory, renal, or hepatic conditions. * Pregnancy. * Blood disorders. (e.g., hemophilia, coagulation disorders, leukemia, thalassemia, sickle cell disease). * Neurological or musculoskeletal conditions affecting muscle tone. * Psychiatric illnesses ( patients with depression in the absence of IBS). * Fibromyalgia. * A history of gastrointestinal surgery or resection, , or other chronic diseases associated with gastrointestinal issues such as inflammatory bowel disease, ulcers, or cancer. * A history of alcohol or drug abuse, abdominal surgery within the past six months. * Recent cervical or cardiac surgery, or recent major trauma.

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Conditions

The condition(s) this trial relates to.

irritable bowel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Irritable bowel syndrome

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Faculty of physical therapy

    Giza, Dokki, 11432, Egypt

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